EN
0
Home > Products > Pharmaceuticals & Life Science > Biotechnology & Diagnostics > S-(4-Nitrobenzyl)-6-thioinosine
S-(4-Nitrobenzyl)-6-thioinosine structure, CAS 38048-32-7

S-(4-Nitrobenzyl)-6-thioinosine

CAS Number38048-32-7

Synonyms{6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine}; NBMPR; 6-[(4-Nitrobenzyl)sulfanyl]-9-(β-D-ribofuranosyl)-9H-purine; S-(4-Nitrobenzyl)-6-thioinosine; EINECS 253-753-4; MFCD00005745; 6-S-[(4-Nitrophenyl)methyl]-6-thioinosine; NBTI; 6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine

Molecular FormulaC17H17N5O6S

Molecular Weight419.41

Purity≥98%

Density1.8±0.1 g/cm3

Boiling Point770.2±70.0 °C at 760 mmHg

Melting Point187-190 °C (lit.)

Flash Point

Appearancesolid

EINECS253-753-4

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9083123 Purity: ≥98%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 38048-32-7 ] Purity: ≥98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number38048-32-7
Catalog No.2A-9083123
Chinese NameS-(4-硝基苄基)-6-硫肌苷
Synonyms{6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine}; NBMPR; 6-[(4-Nitrobenzyl)sulfanyl]-9-(β-D-ribofuranosyl)-9H-purine; S-(4-Nitrobenzyl)-6-thioinosine; EINECS 253-753-4; MFCD00005745; 6-S-[(4-Nitrophenyl)methyl]-6-thioinosine; NBTI; 6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine
Molecular FormulaC17H17N5O6S
Molecular Weight419.41
Purity≥98
Density1.8±0.1 g/cm3
Boiling Point770.2±70.0 °C at 760 mmHg
Melting Point187-190 °C (lit.)
Appearancesolid
Water Solubility0.1 M HCl: slightly soluble
Storage ConditionSealed and stored at 2 ºC -10 ºC
ApplicationNitrobenzylthioinosine is an ENT1 transporter inhibitor that binds to the ENT1 transporter with high affinity. Nitrobenzylthioinosine is a photoaffinity probe used to track adenosine uptake sites in t
EINECS253-753-4
PubChem ID24277723
MDL NumberMFCD00005745
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(SCc4ccc(cc4)[N+]([O-])=O)ncnc23
InChI1S/C17H17N5O6S/c23-5-11-13(24)14(25)17(28-11)21-8-20-12-15(21)18-7-19-16(12)29-6-9-1-3-10(4-2-9)22(26)27/h1-4,7-8,11,13-14,17,23-25H,5-6H2/t11-,13-,14-,17-/m1/s1
InChI KeyDYCJFJRCWPVDHY-LSCFUAHRSA-N
NACRES CodeNA.77
UNSPSC12352202
Hazard Symbolstransportation
MSDSmsds/83123_1_38048_32_7.pdf
BioactivityNitrobenzylthioinosine is an ENT1 transporter inhibitor that binds to ENT1 transporter with high affinity. Nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Nitrobenzylthioinosine can cross the blood-brain barrier[1][2][3]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor Target ENT1 transporter[1] References [1]. Lauri Alanko, et al. Nitrobenzylthioinosine (NBMPR) binding and nucleoside transporter ENT1 mRNA expression after prolonged wakefulness and recovery sleep in the cortex and basal forebrain of rat. J Sleep Res. 2003 Dec;12(4):299-304. [2]. C M Anderson, et al. Ability of nitrobenzylthioinosine to cross the blood-brain barrier in rats. Neurosci Lett. 1996 Nov 29;219(3):191-4. [3]. P J Marangos, et al. [3H]nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Eur J Pharmacol. 1982 Dec 3;85(3-4):359-60. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 770.2±70.0 °C at 760 mmHg Melting Point 187-190 °C(lit.) Molecular Formula C17H17N5O6S Molecular Weight 419.412 Flash Point 419.6±35.7 °C Exact Mass 419.089966 PSA 184.64000 LogP 1.20 Appearance of Characters solid | white Vapour Pressure 0.0±2.8 mmHg at 25°C Index of Refraction 1.808 InChIKey DYCJFJRCWPVDHY-LSCFUAHRSA-N SMILES O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 Storage condition 2-8°C Water Solubility 0.1 M HCl: slightly soluble
Use ofNitrobenzylthioinosine is an ENT1 transporter inhibitor that binds to ENT1 transporter with high affinity. Nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Nitrobenzylthioinosine can cross the blood-brain barrier[1][2][3]. Properties Articles56 Name S-(4-Nitrobenzyl)-6-thioinosine Synonym More Synonyms Nitrobenzylthioinosine Biological Activity Description Nitrobenzylthioinosine is an ENT1 transporter inhibitor that binds to ENT1 transporter with high affinity. Nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Nitrobenzylthioinosine can cross the blood-brain barrier[1][2][3]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor ENT1 transporter[1] References [2]. C M Anderson, et al. Ability of nitrobenzylthioinosine to cross the blood-brain barrier in rats. Neurosci Lett. 1996 Nov 29;219(3):191-4. [3]. P J Marangos, et al. [3H]nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Eur J Pharmacol. 1982 Dec 3;85(3-4):359-60. Chemical & Physical Properties Molecular Formula C17H17N5O6S Exact Mass 419.089966 PSA 184.64000 Appearance of Characters solid | white Index of Refraction 1.808 InChIKey DYCJFJRCWPVDHY-LSCFUAHRSA-N Water Solubility 0.1 M HCl: slightly soluble
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip.
Related Products in Biotechnology & Diagnostics
Adenosine5'-triphosphate,periodateoxidizedsodiumsalt 71997-40-52A-9083069
2'-Deoxyuridine5'-triphosphatetetralithiumsalt 93858-62-92A-9083071
Adenosine2',5'-diphosphateSodiumSalt 108347-94-02A-9083072
3'-ACETYLTHYMIDINE21090-30-22A-9083073
2',3'-DI-O-ACETYLADENOSINE29886-19-92A-0202506
2,3'-Anhydrothymidine 15981-92-72A-9083188
3',5'-Diacetylthymidine 6979-97-12A-9083189
5-Iodouridine 1024-99-32A-9083191
6-Azauridine2',3',5'-triacetate 2169-64-42A-9083192
Boc-D-Glu(OcHex)-OH 133464-27-42A-9083193
Browse all Biotechnology & Diagnostics products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA