CAS Number2946-39-6
Synonyms8-Br-A; 8-Bromoadenine-9-β-D-ribofuranoside; 8-Bromoadenosine; (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-BROMO-D-ADENOSINE; 6-AMINO-8-BROMOPURINE RIBOSIDE; 8-bromo-adenosine; MFCD00005733; EINECS 220-959-0
Molecular FormulaC10H12BrN5O4
Molecular Weight426.12
Purity≥98%
Density2.5±0.1 g/cm3
Boiling Point717.7±70.0 °C at 760 mmHg
Melting Point210-212 °C (dec.)(lit.)
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2946-39-6 |
| Catalog No. | 2A-9007010 |
| Chinese Name | 8-溴腺苷 |
| Synonyms | 8-Br-A; 8-Bromoadenine-9-β-D-ribofuranoside; 8-Bromoadenosine; (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-BROMO-D-ADENOSINE; 6-AMINO-8-BROMOPURINE RIBOSIDE; 8-bromo-adenosine; MFCD00005733; EINECS 220-959-0 |
| Molecular Formula | C10H12BrN5O4 |
| Molecular Weight | 426.12 |
| Purity | ≥98 |
| Density | 2.5±0.1 g/cm3 |
| Boiling Point | 717.7±70.0 °C at 760 mmHg |
| Melting Point | 210-212 °C (dec.)(lit.) |
| Appearance | powder |
| Storage Condition | This product should be sealed and stored dry and b |
| Application | 8-Bromoadenosine is an adenosine analog. Adenosine analogs primarily function as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products include adenosi |
| HTC | 2933.59.9550 |
| PubChem ID | 24891684 |
| MDL Number | MFCD00056945 |
| SMILES | Nc1ncnc2n(C3OC(COP(O)(O)=O)C(O)C3O)c(Br)nc12 |
| InChI | 1S/C10H13BrN5O7P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,13,14)(H2,19,20,21) |
| InChI Key | DNPIJKNXFSPNNY-UHFFFAOYSA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| Hazard Symbols | Transport |
| MSDS | msds/7010_1_2946_39_6.pdf |
| Bioactivity | 8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. Chemical & Physical Properties Density 2.5±0.1 g/cm3 Boiling Point 717.7±70.0 °C at 760 mmHg Melting Point 210-212 °C (dec.)(lit.) Molecular Formula C10H12BrN5O4 Molecular Weight 346.14 Flash Point 387.8±35.7 °C Exact Mass 345.007263 PSA 139.54000 LogP -0.30 Vapour Pressure 0.0±2.4 mmHg at 25°C Index of Refraction 1.941 InChIKey VJUPMOPLUQHMLE-UUOKFMHZSA-N SMILES Nc1ncnc2c1nc(Br)n2C1OC(CO)C(O)C1O Storage condition 2-8°C |
| Use of | 8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. Properties Articles40 Name 8-bromoadenosine Synonym More Synonyms 8-Bromoadenosine Biological Activity Description 8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. Chemical & Physical Properties Molecular Formula C10H12BrN5O4 Exact Mass 345.007263 PSA 139.54000 LogP -0.30 Index of Refraction 1.941 InChIKey VJUPMOPLUQHMLE-UUOKFMHZSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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