CAS Number2004-07-1
Synonyms(−)-2-Amino-6-chloropurine riboside 6-Chloroguanine riboside; 6-Chloroguanineriboside; 2-Amino-6-chloro-9-(β-D-ribofuranosyl)purine; 6-Chloro-9-(β-D-ribofuranosyl)-9H-purin-2-amine; EINECS 217-905-3; (−)-2-Amino-6-chloropurine riboside; 6-CHLOROGUANOSINE; 2-Amino-6-chloropurine Riboside; 6-Chloroguanine nucleoside; 6-CHLOROADENOSINE; 6-Chloroguanosine2; MFCD00005735; 2-Amino-6-chloropurine-9--D-riboside; 6-Chloroguanine riboside; 2-amino-6-chloro purineriboside
Molecular FormulaC10H12O4N5Cl1
Molecular Weight301.69
Purity98%
Density2.2±0.1 g/cm3
Boiling Point729.9±70.0 °C at 760 mmHg
Melting Point165-167 °C (dec.)(lit.)
AppearanceWhite to off-white crystalline powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2004-07-1 |
| Catalog No. | 2A-9006803 |
| Chinese Name | 6-氯鸟嘌呤核苷 |
| Synonyms | (−)-2-Amino-6-chloropurine riboside 6-Chloroguanine riboside; 6-Chloroguanineriboside; 2-Amino-6-chloro-9-(β-D-ribofuranosyl)purine; 6-Chloro-9-(β-D-ribofuranosyl)-9H-purin-2-amine; EINECS 217-905-3; (−)-2-Amino-6-chloropurine riboside; 6-CHLOROGUANOSINE; 2-Amino-6-chloropurine Riboside; 6-Chloroguanine nucleoside; 6-CHLOROADENOSINE; 6-Chloroguanosine2; MFCD00005735; 2-Amino-6-chloropurine-9--D-riboside; 6-Chloroguanine riboside; 2-amino-6-chloro purineriboside |
| Molecular Formula | C10H12O4N5Cl1 |
| Molecular Weight | 301.69 |
| Purity | 98 |
| Density | 2.2±0.1 g/cm3 |
| Boiling Point | 729.9±70.0 °C at 760 mmHg |
| Melting Point | 165-167 °C (dec.)(lit.) |
| Appearance | White to off-white crystalline powder |
| Storage Condition | −20°C |
| Application | 6-Chloroguanosine (6-chloroguanosine) is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in t |
| MDL Number | MFCD00005735 |
| SMILES | Nc1nc(Cl)c2ncn(C3OC(CO)C(O)C3O)c2n1 |
| InChI | InChI=1S/C10H12ClN5O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15) |
| InChI Key | TXWHPSZYRUHEGT-VKJDSPIKSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/6803_1_2004_07_1.pdf |
| Bioactivity | 6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Density 2.2±0.1 g/cm3 Boiling Point 729.9±70.0 °C at 760 mmHg Melting Point 165-167 °C (dec.)(lit.) Molecular Formula C10H12ClN5O4 Molecular Weight 301.69 Flash Point 395.2±35.7 °C Exact Mass 301.057770 PSA 139.54000 LogP -0.59 Vapour Pressure 0.0±2.5 mmHg at 25°C Index of Refraction 1.912 InChIKey TXWHPSZYRUHEGT-VKJDSPIKSA-N SMILES Nc1nc(Cl)c2ncn(C3OC(CO)C(O)C3O)c2n1 Storage condition −20°C |
| Use of | 6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name 2-Amino-6-chloropurine-9-riboside Synonym More Synonyms 6-Chloroguanineriboside Biological Activity Description 6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Exact Mass 301.057770 PSA 139.54000 LogP -0.59 Index of Refraction 1.912 InChIKey TXWHPSZYRUHEGT-VKJDSPIKSA-N SMILES Nc1nc(Cl)c2ncn(C3OC(CO)C(O)C3O)c2n1 |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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