| Chemical & Physical Properties | |
|---|---|
| CAS Number | 480449-70-5 |
| Catalog No. | 2A-9057413 |
| Chinese Name | 艾多沙班 |
| Synonyms | Edoxaban; Lixiana; Savaysa; EthanediaMide,N1-(5-chlo... |
| Molecular Formula | C24H30ClN7O4S |
| Molecular Weight | 548.07 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Storage Condition | 2-8°C |
| Application | Edoxaban (DU-176) is an oral FXa inhibitor clinically developed for stroke prevention. |
| HTC | 2934999090 |
| MDL Number | C24H30ClN7O4S |
| SMILES | CN1CCc2nc(C(=O)NC3CC(C(=O)N(C)C)CCC3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1 |
| InChI Key | HGVDHZBSSITLCT-JLJPHGGASA-N |
| MSDS | msds/57413_1_480449_70_5.pdf |
| Use of | Properties Name edoxaban Synonym More Synonyms edoxaban Biological Activity Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa Research Areas >> Cardiovascular Disease References [1]. Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. [Epub ahead of print] [2]. Mendell J, Noveck RJ, Shi M. Pharmacokinetics of the direct factor Xa inhibitor edoxaban and digoxin administered alone and in combination. J Cardiovasc Pharmacol. 2012 Oct;60(4):335-41. [3]. Bathala MS, Masumoto H, Oguma T, Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos. 2012 Dec;40(12):2250-5. Chemical & Physical Properties Exact Mass 547.176880 PSA 164.87000 Index of Refraction 1.646 InChIKey HGVDHZBSSITLCT-JLJPHGGASA-N Safety Information Hazard Codes Xn HS Code 2934999090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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