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Pazopanib

Name: Pazopanib
Brand: 2A Biotech
SKU: 2A-9057232

CAS Number444731-52-6

Synonyms5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzenesulfonamide; Pazopanib(GW786034); 5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide; Pazopanib

Molecular FormulaC21H23N7O2S

Molecular Weight437.52

Purity98.00%

Density1.4±0.1 g/cm3

Boiling Point728.8±70.0 °C at 760 mmHg

Melting Point285-289°C (dec.)

Appearancesolid

MSDSChinese English

Cat. No.: 2A-9057232 Purity: 98.00%

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Quality Control of [ 444731-52-6 ] Purity: 98.00% SDS Specification MoL

Chemical & Physical Properties
CAS Number	444731-52-6
Catalog No.	2A-9057232
Chinese Name	帕唑帕尼
Synonyms	5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzenesulfonamide; Pazopanib(GW786034); 5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide; Pazopanib
Molecular Formula	C21H23N7O2S
Molecular Weight	437.52
Purity	98.00
Density	1.4±0.1 g/cm3
Boiling Point	728.8±70.0 °C at 760 mmHg
Melting Point	285-289°C (dec.)
Appearance	solid
Storage Condition	Refrigerator
Application	Pazopanib (GW786034) is a multi-target inhibitor with IC50s of 10, 30, 47, 84, 74, 140, and 146 nM for inhibiting VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms respectively.
PubChem ID	329796891
MDL Number	MFCD11616589
SMILES	CN1N=C2C=C(N(C3=NC(NC4=CC=C(C(S(N)(=O)=O)=C4)C)=NC=C3)C)C=CC2=C1C
InChI	1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
InChI Key	CUIHSIWYWATEQL-UHFFFAOYSA-N
NACRES Code	NA.21
UNSPSC	12352200
MSDS	msds/57232_1_444731_52_6.pdf
Transport Info	Product Name: Pazopanib

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