
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 475207-59-1 |
| Catalog No. | 2A-9057346 |
| Chinese Name | 甲苯磺酸索拉非尼 |
| Synonyms | Sorafenib Tosylate; Bay 43-9006; Sorafenib (Tosylate) |
| Molecular Formula | C28H24ClF3N4O6S |
| Molecular Weight | 637.03 |
| Purity | 98.00 |
| Density | 1.454 g/cm3 |
| Boiling Point | 523.3ºC at 760 mmHg |
| Storage Condition | 2~8℃ |
| Application | Sorafenib tosylate is a potent multi-kinase inhibitor with IC50s of 6 nM, 20 nM and 22 nM for Raf-1, B-Raf and VEGFR-3 respectively. |
| MDL Number | MFCD08235032 |
| SMILES | FC(F)(F)c2c(ccc(c2)NC(=O)Nc3ccc(cc3)Oc4cc(ncc4)C(=O)NC)Cl.[S](=O)(=O)([O-])c1ccc(cc1)C.[H+] |
| InChI | 1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10) |
| InChI Key | IVDHYUQIDRJSTI-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/57346_1_475207_59_1.pdf |
| Transport Info | Product Name: Sorafenib Tosylate |
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