CAS Number55750-63-5
Synonyms1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione; MFCD00043043; 1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione; (2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate; N-succinimidyl-6-maleimidocaproate; 6-Maleimidohexanoic acid N-hydroxysuccinimide ester; MCOSU; EMCS
Molecular FormulaC14H16N2O6
Molecular Weight308.29
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point480.6±47.0 °C at 760 mmHg
Melting Point70-73 °C(lit.)
AppearanceWhite to cream colored crystals
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 55750-63-5 |
| Catalog No. | 2A-9044483 |
| Chinese Name | 6-(马来酰亚胺基)己酸琥珀酰亚胺酯 |
| Synonyms | 1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione; MFCD00043043; 1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione; (2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate; N-succinimidyl-6-maleimidocaproate; 6-Maleimidohexanoic acid N-hydroxysuccinimide ester; MCOSU; EMCS |
| Molecular Formula | C14H16N2O6 |
| Molecular Weight | 308.29 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 480.6±47.0 °C at 760 mmHg |
| Melting Point | 70-73 °C(lit.) |
| Appearance | White to cream colored crystals |
| Water Solubility | chloroform: 100mg/mL |
| Storage Condition | Seal and store at -20ºC |
| Application | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (ECMS) is a commonly used protecting group in antibody drug conjugates (ADCs). |
| HTC | 2925190090 |
| PubChem ID | 329759804 |
| SMILES | O=C(CCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O |
| InChI | InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2 |
| InChI Key | VLARLSIGSPVYHX-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. Related Catalog Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Cancer Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 480.6±47.0 °C at 760 mmHg Melting Point 70-73 °C(lit.) Molecular Formula C14H16N2O6 Molecular Weight 308.287 Flash Point 244.5±29.3 °C Exact Mass 308.100830 PSA 101.06000 LogP -0.81 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.577 InChIKey VLARLSIGSPVYHX-UHFFFAOYSA-N SMILES O=C(CCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O Storage condition −20°C Water Solubility chloroform: 100mg/mL |
| Use of | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. Properties Articles14 Name N-Succinimidyl 6-maleimidohexanoate Synonym More Synonyms N-Succinimidyl 6-maleimidohexanoate Biological Activity Description 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. Related Catalog Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Cancer Chemical & Physical Properties Molecular Formula C14H16N2O6 Exact Mass 308.100830 PSA 101.06000 LogP -0.81 Index of Refraction 1.577 InChIKey VLARLSIGSPVYHX-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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