CAS Number55750-61-3
Synonyms(2,5-dioxopyrrolidin-1-yl) 2-(2,5-dioxopyrrol-1-yl)acetate; MFCD00133523; 1-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl}-1H-pyrrole-2,5-dione; N-Succinimidyl maleimidoacetate
Molecular FormulaC10H8N2O6
Molecular Weight252.18
Purity≥95%
Density1.6±0.1 g/cm3
Boiling Point430.1±47.0 °C at 760 mmHg
Melting Point174-175ºC
AppearanceWhite to light white powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 55750-61-3 |
| Catalog No. | 2A-9044481 |
| Chinese Name | 马来酰亚胺基乙酸N-琥珀酰亚胺酯 |
| Synonyms | (2,5-dioxopyrrolidin-1-yl) 2-(2,5-dioxopyrrol-1-yl)acetate; MFCD00133523; 1-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl}-1H-pyrrole-2,5-dione; N-Succinimidyl maleimidoacetate |
| Molecular Formula | C10H8N2O6 |
| Molecular Weight | 252.18 |
| Purity | ≥95 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 430.1±47.0 °C at 760 mmHg |
| Melting Point | 174-175ºC |
| Appearance | White to light white powder |
| Storage Condition | Sealed, store at -20 ºC |
| Application | AMAS is a heterobifunctional cross-linker with NHS ester and maleimide groups, which allows the covalent binding of amine- and thiol-containing molecules and is a common linking bridge for ADCs. |
| HTC | 2925190090 |
| PubChem ID | 24896882 |
| MDL Number | MFCD00133523 |
| SMILES | O=C(N1CC(ON2C(CCC2=O)=O)=O)C=CC1=O |
| InChI | 1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2 |
| InChI Key | TYKASZBHFXBROF-UHFFFAOYSA-N |
| NACRES Code | NC.07 |
| UNSPSC | 12352106 |
| Hazard Symbols | transportation |
| MSDS | msds/44481_1_55750_61_3.pdf |
| Bioactivity | AMAS is a heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Alkyl/ether Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 430.1±47.0 °C at 760 mmHg Melting Point 174-175ºC Molecular Formula C10H8N2O6 Molecular Weight 252.180 Flash Point 213.9±29.3 °C Exact Mass 252.038239 PSA 101.06000 LogP -2.21 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.620 InChIKey TYKASZBHFXBROF-UHFFFAOYSA-N SMILES O=C(CN1C(=O)C=CC1=O)ON1C(=O)CCC1=O |
| Use of | AMAS is a heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules. Properties Name Maleimidoacetic Acid N-Hydroxysuccinimide Ester Synonym More Synonyms N-Succinimidyl maleimidoacetate Biological Activity Description AMAS is a heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Alkyl/ether Chemical & Physical Properties Molecular Formula C10H8N2O6 Exact Mass 252.038239 PSA 101.06000 LogP -2.21 Index of Refraction 1.620 InChIKey TYKASZBHFXBROF-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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