CAS Number501-97-3
Synonyms4-hydroxy-benzenepropanoic acid; MFCD00002778; 3-(p-hydroxyphenyl)propionic acid; 4-Hydroxyhydrocinnamic Acid; 3-(4-Hydroxyphenyl)propanoic acid; Phloretic acid; 3-(p-Hydroxyphenyl)propionic acid,Phloretic acid; 3-(para-Hydroxyphenyl)propionic acid; 3-(4-Hydroxyphenyl)-propionic acid; 3-(4-Hydroxyphenyl)propionic acid; b-(p-Hydroxyphenyl)propionic acid; p-hydroxy-hydrocinnamic acid; EINECS 207-931-3
Molecular FormulaHOC6H4CH2CH2CO2H
Molecular Weight166.17
Purity98%
Density1.3±0.1 g/cm3
Boiling Point352.4±17.0 °C at 760 mmHg
Melting Point129-131 °C (lit.)
AppearanceOff-white-yellow crystals
EINECS207-931-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 501-97-3 |
| Catalog No. | 2A-9003621 |
| Chinese Name | 对羟基苯丙酸 |
| Synonyms | 4-hydroxy-benzenepropanoic acid; MFCD00002778; 3-(p-hydroxyphenyl)propionic acid; 4-Hydroxyhydrocinnamic Acid; 3-(4-Hydroxyphenyl)propanoic acid; Phloretic acid; 3-(p-Hydroxyphenyl)propionic acid,Phloretic acid; 3-(para-Hydroxyphenyl)propionic acid; 3-(4-Hydroxyphenyl)-propionic acid; 3-(4-Hydroxyphenyl)propionic acid; b-(p-Hydroxyphenyl)propionic acid; p-hydroxy-hydrocinnamic acid; EINECS 207-931-3 |
| Molecular Formula | HOC6H4CH2CH2CO2H |
| Molecular Weight | 166.17 |
| Purity | 98 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 352.4±17.0 °C at 760 mmHg |
| Melting Point | 129-131 °C (lit.) |
| Appearance | Off-white-yellow crystals |
| Water Solubility | slightly soluble |
| Storage Condition | Store sealed and placed in a ventilated, dry envir |
| Application | Desaminotyrosine is a microbiome-associated metabolite that blocks influenza by amplifying type I interferon signaling. |
| EINECS | 207-931-3 |
| HTC | 2916399090 |
| PubChem ID | 24895679 |
| MDL Number | MFCD00002778 |
| SMILES | OC(=O)CCc1ccc(O)cc1 |
| InChI | 1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12) |
| InChI Key | NMHMNPHRMNGLLB-UHFFFAOYSA-N |
| Beilstein/REAXYS | 2209841 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| Risk Codes | R36/37/38 |
| Safety Description | S26;S37/39 |
| MSDS | msds/3621_1_501_97_3.pdf |
| Bioactivity | Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection Natural Products >> Saccharides and Glycosides Target Human Endogenous Metabolite In Vivo Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice[1]. Animal Admin Mice[1] Indicated mice receive 200 mM Desaminotyrosine dissolved in Kool-Aid in the drinking water (control animals receive Kool-Aid alone). Indicated mice receive poly(IC) injections of 1 mg/kg for vancomycin, neomycin, ampicillin, and metronidazole (VNAM) treated mice or 5 mg/kg for all other mice intraperitoneally daily for 4 days, and then mice are scarified on day five at which time serum is collected[1]. References [1]. Steed AL, et al. The microbial metabolite desaminotyrosine protects from influenza through type I interferon. Science. 2017 Aug 4;357(6350):498-502. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 352.4±17.0 °C at 760 mmHg Melting Point 129-131 °C(lit.) Molecular Formula C9H10O3 Molecular Weight 166.174 Flash Point 181.1±17.4 °C Exact Mass 166.062988 PSA 57.53000 LogP 1.10 Vapour Pressure 0.0±0.8 mmHg at 25°C Index of Refraction 1.580 InChIKey NMHMNPHRMNGLLB-UHFFFAOYSA-N SMILES O=C(O)CCc1ccc(O)cc1 Storage condition 2-8°C Water Solubility slightly soluble |
| Use of | Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. Properties Articles39 Name phloretic acid Synonym More Synonyms Desaminotyrosine Biological Activity Description Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection Natural Products >> Saccharides and Glycosides Human Endogenous Metabolite References [1]. Steed AL, et al. The microbial metabolite desaminotyrosine protects from influenza through type I interferon. Science. 2017 Aug 4;357(6350):498-502. Chemical & Physical Properties Molecular Formula C9H10O3 Exact Mass 166.062988 PSA 57.53000 Index of Refraction 1.580 InChIKey NMHMNPHRMNGLLB-UHFFFAOYSA-N Water Solubility slightly soluble |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 3-(4-Ethoxybenzoyl)acrylic acid | 29582-31-8 | 2A-9003614 |
| 3-(4-Fluorobenzoyl)propionic acid | 366-77-8 | 2A-9003615 |
| 3-(4-Fluorophenoxy)propionic acid | 1579-78-8 | 2A-9003617 |
| 3-(4-Fluorophenyl)propionic acid | 459-31-4 | 2A-9003619 |
| 3-(4-Fluorophenylthio)-2-hydroxy-2-methylpropanoic acid | 339530-91-5 | 2A-9003620 |
| 3-(4-Methoxyphenyl)propanal | 20401-88-1 | 2A-9003623 |
| 3-(4-Methoxyphenyl)propionic acid | 1929-29-9 | 2A-9003624 |
| 3-(4-Nitrophenoxy)benzoic acid | 2A-103625 | 2A-9003625 |
| 3-(4-Nitrophenyl)propanoic acid | 16642-79-8 | 2A-9003626 |
| 3-(4-Pyridyl)acrylic acid | 5337-79-1 | 2A-9003628 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS