CAS Number515-69-5
SynonymsMFCD03846910; rel-(2R)-6-Methyl-2-[(1R)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol; )-α-Bisabolol; a-Bisabolol; α-Bisabolol; dl-a-Bisabolol; (±)-α-Bisabolol; (2R)-6-Methyl-2-[(1R)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol; 6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol; EINECS 208-205-9; (2R)-6-Methyl-2-[(1R)-4-methyl-3-cyclohexen-1-yl]-5-hepten-2-ol; Dragosantol; (R*,R*)-6-Dethyl-2-(4-methyl-3-cyclohexen-1-yl)-5-Hepten-2-ol; (±)-a-Bisabolol
Molecular FormulaC15H26O1
Molecular Weight222.37
Purity98.00%
Density0.9±0.1 g/cm3
Boiling Point314.5±11.0 °C at 760 mmHg
AppearanceColorless or straw-yellow mucus liquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 515-69-5 |
| Catalog No. | 2A-9022428 |
| Chinese Name | 红没药醇 |
| Synonyms | MFCD03846910; rel-(2R)-6-Methyl-2-[(1R)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol; )-α-Bisabolol; a-Bisabolol; α-Bisabolol; dl-a-Bisabolol; (±)-α-Bisabolol; (2R)-6-Methyl-2-[(1R)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol; 6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol; EINECS 208-205-9; (2R)-6-Methyl-2-[(1R)-4-methyl-3-cyclohexen-1-yl]-5-hepten-2-ol; Dragosantol; (R*,R*)-6-Dethyl-2-(4-methyl-3-cyclohexen-1-yl)-5-Hepten-2-ol; (±)-a-Bisabolol |
| Molecular Formula | C15H26O1 |
| Molecular Weight | 222.37 |
| Purity | 98.00 |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 314.5±11.0 °C at 760 mmHg |
| Appearance | Colorless or straw-yellow mucus liquid |
| Storage Condition | Store in a cool, dry, well-ventilated warehouse. K |
| Application | Alpha-Bisabolol is a non-toxic sesquiterpene alcohol found in natural essential oils that has anti-cancer activity. alpha-Bisabolol exerts anticancer effects on A549 NSCLC cells by inducing cell cycle |
| HTC | 29061900 |
| MDL Number | MFCD00129082 |
| SMILES | CC(C)=CCCC(C)(O)C1CC=C(C)CC1 |
| InChI | InChI=1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15-/m0/s1 |
| InChI Key | RGZSQWQPBWRIAQ-LOACHALJSA-N |
| Hazard Symbols | 6.1 |
| MSDS | msds/22428_1_515_69_5.pdf |
| Bioactivity | alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Wu S, et al. Anticancer effects of α-Bisabolol in human non-small cell lung carcinoma cells are mediated via apoptosis induction, cell cycle arrest, inhibition of cell migration and invasion and upregulation of P13K/AKT signalling pathway. J BUON. 2018 Sep-Oct;23(5):1407-1412. [2]. Cavalieri E, et al. alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells. Biochem Biophys Res Commun. 2004 Mar 12;315(3):589-94. Chemical & Physical Properties Density 0.9±0.1 g/cm3 Boiling Point 314.5±11.0 °C at 760 mmHg Molecular Formula C15H26O Molecular Weight 222.366 Flash Point 113.2±15.6 °C Exact Mass 222.198364 PSA 20.23000 LogP 5.07 Vapour Pressure 0.0±1.5 mmHg at 25°C Index of Refraction 1.494 InChIKey RGZSQWQPBWRIAQ-LOACHALJSA-N SMILES CC(C)=CCCC(C)(O)C1CC=C(C)CC1 Stability Stable. Combustible. Incompatible with strong oxidizing agents. |
| Use of | alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2]. Properties Name alpha-Bisabolol Synonym More Synonyms alpha-Bisabolol Biological Activity Description alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Wu S, et al. Anticancer effects of α-Bisabolol in human non-small cell lung carcinoma cells are mediated via apoptosis induction, cell cycle arrest, inhibition of cell migration and invasion and upregulation of P13K/AKT signalling pathway. J BUON. 2018 Sep-Oct;23(5):1407-1412. [2]. Cavalieri E, et al. alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells. Biochem Biophys Res Commun. 2004 Mar 12;315(3):589-94. Chemical & Physical Properties Molecular Formula C15H26O Exact Mass 222.198364 PSA 20.23000 Index of Refraction 1.494 InChIKey RGZSQWQPBWRIAQ-LOACHALJSA-N Stability Stable. Combustible. Incompatible with strong oxidizing agents. |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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