CAS Number529-84-0
Synonyms6,7-Dihydroxy-4-methylcoumarin; 4-Methylesculetin; EINECS 208-470-0; MFCD00006859; 6,7-Dihydroxy-4-methyl-2H-chromen-2-one; 6,7-dihydroxy-4-methylchromen-2-one
Molecular FormulaC10H8O4
Molecular Weight192.17
Purity98.00%
Density1.5±0.1 g/cm3
Boiling Point455.5±45.0 °C at 760 mmHg
Melting Point274-276 °C(lit.)
Appearanceyellow needle crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 529-84-0 |
| Catalog No. | 2A-9022551 |
| Chinese Name | 4-甲基七叶亭 |
| Synonyms | 6,7-Dihydroxy-4-methylcoumarin; 4-Methylesculetin; EINECS 208-470-0; MFCD00006859; 6,7-Dihydroxy-4-methyl-2H-chromen-2-one; 6,7-dihydroxy-4-methylchromen-2-one |
| Molecular Formula | C10H8O4 |
| Molecular Weight | 192.17 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 455.5±45.0 °C at 760 mmHg |
| Melting Point | 274-276 °C(lit.) |
| Appearance | yellow needle crystal |
| Water Solubility | DMF: soluble |
| Storage Condition | Store in a cool, dry, well-ventilated warehouse. K |
| Application | 4-Methylesculetin is an orally available natural coumarin derivative with potent antioxidant and anti-inflammatory activities. 4-Methylesculetin inhibits the activity of myeloperoxidase and reduces IL |
| HTC | 2932209090 |
| MDL Number | C10H8O4 |
| SMILES | Cc1cc(=O)oc2cc(O)c(O)cc12 |
| InChI Key | KVOJTUXGYQVLAJ-UHFFFAOYSA-N |
| MSDS | msds/22551_1_529_84_0.pdf |
| Bioactivity | 4-Methylesculetin is an orally active natural coumarin derivative, with potent anti-oxidant and anti-inflammatory activities. 4-Methylesculetin inhibits myeloperoxidase activity and reduces IL-6 level[1]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. Witaicenis A, et al. 4-methylesculetin, a coumarin derivative, ameliorates dextran sulfate sodium-induced intestinal inflammation. Chem Biol Interact. 2018 Jan 25;280:59-63. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 455.5±45.0 °C at 760 mmHg Melting Point 274-276 °C(lit.) Molecular Formula C10H8O4 Molecular Weight 192.168 Flash Point 190.8±22.2 °C Exact Mass 192.042252 PSA 70.67000 LogP 2.08 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.652 InChIKey KVOJTUXGYQVLAJ-UHFFFAOYSA-N SMILES Cc1cc(=O)oc2cc(O)c(O)cc12 Storage condition 2-8°C Water Solubility DMF: soluble |
| Use of | Properties Name 4-methylesculetin Synonym More Synonyms 6,7-Dihydroxy-4-methyl-2H-chromen-2-one Biological Activity Related Catalog Research Areas >> Inflammation/Immunology References [1]. Witaicenis A, et al. 4-methylesculetin, a coumarin derivative, ameliorates dextran sulfate sodium-induced intestinal inflammation. Chem Biol Interact. 2018 Jan 25;280:59-63. Chemical & Physical Properties Molecular Formula C10H8O4 Exact Mass 192.042252 PSA 70.67000 Index of Refraction 1.652 InChIKey KVOJTUXGYQVLAJ-UHFFFAOYSA-N Water Solubility DMF: soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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