EN
0
Home > Products > Natural Products & Standards > Botanical Reference Standards > 3-Indoxyl-beta-D-glucopyranoside
3-Indoxyl-beta-D-glucopyranoside structure, CAS 487-60-5

3-Indoxyl-beta-D-glucopyranoside

CAS Number487-60-5

SynonymsIndikan; Plant indican; Indican; 3-Indolyl-b-D-glucopyranoside; 3-Indole-D-glucoside Hydrate; Indoxyl-D-glucoside Hydrate; Indoxyl β-D-glucoside; 1H-Indol-3-yl β-D-glucopyranoside; 1H-Indol-3-yl β-glucopyranoside; Indoxyl-b-D-glucoside; 3-Indolyl-D-glucoside Hydrate; Indoxyl-β-D-glucoside; Indican Hydrate; Uroxanthin; 3-Indoxyl-beta-D-glucopyranoside; 3-Indoxyl-D-glucoside Hydrate; 3-(b-Glucosido)indole; 1H-Indol-3-yl-b-D-glucopyranoside; MFCD00047169; 3-Indoxyl-β-D-glucopyranoside; β-D-Glucopyranoside, 1H-indol-3-yl

Molecular FormulaC14H17NO6

Molecular Weight295.29

Purity≥97%

Density1.6±0.1 g/cm3

Boiling Point606.7±55.0 °C at 760 mmHg

Melting Point57-58ºC

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9022202 Purity: ≥97%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 487-60-5 ] Purity: ≥97% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number487-60-5
Catalog No.2A-9022202
Chinese Name吲哚基 β-D-葡萄糖苷
SynonymsIndikan; Plant indican; Indican; 3-Indolyl-b-D-glucopyranoside; 3-Indole-D-glucoside Hydrate; Indoxyl-D-glucoside Hydrate; Indoxyl β-D-glucoside; 1H-Indol-3-yl β-D-glucopyranoside; 1H-Indol-3-yl β-glucopyranoside; Indoxyl-b-D-glucoside; 3-Indolyl-D-glucoside Hydrate; Indoxyl-β-D-glucoside; Indican Hydrate; Uroxanthin; 3-Indoxyl-beta-D-glucopyranoside; 3-Indoxyl-D-glucoside Hydrate; 3-(b-Glucosido)indole; 1H-Indol-3-yl-b-D-glucopyranoside; MFCD00047169; 3-Indoxyl-β-D-glucopyranoside; β-D-Glucopyranoside, 1H-indol-3-yl
Molecular FormulaC14H17NO6
Molecular Weight295.29
Purity≥97
Density1.6±0.1 g/cm3
Boiling Point606.7±55.0 °C at 760 mmHg
Melting Point57-58ºC
Appearancepowder
Water SolubilityH2O: 0.1 M at 20 °C, clear to slightly hazy, color
Storage ConditionStore sealed and placed in a ventilated, dry envir
ApplicationIndian (indoloxy-β-D-glucoside) is a glycoside of indoleoxy and is the precursor of the dyes diethylene glycol and indirubin. Indican has a major metabolite, indolyloxy sulfate (IS). IS is a uremic to
HTC2934999090
PubChem ID24896044
MDL NumberMFCD00047169
SMILESOC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O
InChI1S/C14H17NO6/c16-6-10-11(17)12(18)13(19)14(21-10)20-9-5-15-8-4-2-1-3-7(8)9/h1-5,10-19H,6H2/t10-,11-,12+,13-,14-/m1/s1
InChI KeyXVARCVCWNFACQC-RKQHYHRCSA-N
NACRES CodeNA.21
UNSPSC12352201
MSDSmsds/22202_1_487_60_5.pdf
BioactivityIndican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vivo Indican ((Indoxyl-β-D-glucoside; oral; 20, 40 mg/kg; single dose) increases the systemic exposure and MRT of MTX through inhibition on multiple anion transporters including OAT 1, OAT 3 and MRP 4 by the major metabolite IS[1]. Animal Model: Male Spraguee Dawley rats weighing 330-400 g[1] Dosage: 20, 40 mg/kg Administration: Orally Result: Increased the systemic exposure and multidrug resistance-associated protein (MRP) of Methotrexate (MTX; 5.0 mg/kg). References [1]. Shiuan-Pey Lin, et al. Transporter-mediated interaction of indican and methotrexate in rats. J Food Drug Anal. 2018 Apr;26(2S):S133-S140. [2]. Yu-Chi Hou, et al. Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-beta-D-glucoside (indican) in rats. Toxicon. 2008 Sep 1;52(3):440-4. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 606.7±55.0 °C at 760 mmHg Melting Point 57-58ºC Molecular Formula C14H17NO6 Molecular Weight 295.288 Flash Point 320.7±31.5 °C Exact Mass 295.105591 PSA 115.17000 LogP -0.75 Vapour Pressure 0.0±1.8 mmHg at 25°C Index of Refraction 1.715 InChIKey XVARCVCWNFACQC-RKQHYHRCSA-N SMILES OCC1OC(Oc2c[nH]c3ccccc23)C(O)C(O)C1O Storage condition −20°C Water Solubility H2O: 0.1 M at 20 °C, clear to slightly hazy, colorless to faint yellow-green
Use ofIndican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4[1][2]. Properties Name indican Synonym More Synonyms Indican Biological Activity Description Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Shiuan-Pey Lin, et al. Transporter-mediated interaction of indican and methotrexate in rats. J Food Drug Anal. 2018 Apr;26(2S):S133-S140. [2]. Yu-Chi Hou, et al. Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-beta-D-glucoside (indican) in rats. Toxicon. 2008 Sep 1;52(3):440-4. Chemical & Physical Properties Molecular Formula C14H17NO6 Exact Mass 295.105591 PSA 115.17000 LogP -0.75 Index of Refraction 1.715 InChIKey XVARCVCWNFACQC-RKQHYHRCSA-N
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified
Related Products in Botanical Reference Standards
Aloe-emodin481-72-12A-9022157
Kaempferitrin482-38-22A-9022161
Afzelin482-39-32A-9022162
Isoimperatorin482-45-12A-9022164
(+)-Bicuculline485-49-42A-9022183
L-Epicatechin490-46-02A-9022218
Quercetin-7-glucoside491-50-92A-9022227
Emodin anthrone491-60-12A-9022228
Baicalein491-67-82A-9022229
Luteolin491-70-32A-9022230
Browse all Botanical Reference Standards products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA