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10,11-methylenedioxycamptothecin

Name: 10,11-methylenedioxycamptothecin
Brand: 2A Biotech
SKU: 2A-3186843

CAS Number135415-73-5

Synonyms10,11-methylenedioxycamptothecin; 10,11-methylenedioxy-20(S)-camptothecin; 10,11-methlyenedioxycamptothecin

Molecular FormulaC21H16O6N2

Molecular Weight392.37

Density1.64g/cm3

Boiling Point812.1ºC at 760mmHg

Appearancesolid

Cat. No.: 2A-3186843 Purity:

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Quality Control of [ 135415-73-5 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	135415-73-5
Catalog No.	2A-3186843
Chinese Name	(S)-7-乙基-7-羟基-7H-[1,3]二氧杂环戊烯并[4,5-g]吡喃并[3',4':6,7]吲哚并[1,2-b]喹啉-8,11(10H,13H)-二酮
Synonyms	10,11-methylenedioxycamptothecin; 10,11-methylenedioxy-20(S)-camptothecin; 10,11-methlyenedioxycamptothecin
Molecular Formula	C21H16O6N2
Molecular Weight	392.37
Density	1.64g/cm3
Boiling Point	812.1ºC at 760mmHg
Appearance	solid
Storage Condition	2-8°C, sealed, dry
Application	FL118 (10,11-(methylenedioxy)-20(S)-camptothecin (HY-16560) analogue is a potent orally active survivin inhibitor. FL118 binds to the oncoprotein DDX5 (p68), dephosphorylates and degrades DDX5. FL118
PubChem ID	497235
MDL Number	MFCD29078463
SMILES	CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5cc6OCOc6cc5nc34)C2=O
InChI	InChI=1S/C21H16N2O6/c1-2-21(26)13-5-15-18-11(7-23(15)19(24)12(13)8-27-20(21)25)3-10-4-16-17(29-9-28-16)6-14(10)22-18/h3-6,26H,2,7-9H2,1H3/t21-/m0/s1
InChI Key	InChIKey=RPFYDENHBPRCTN-NRFANRHFSA-N
Transport Info	Product name: FL118

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