
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 437742-34-2 |
| Catalog No. | 2A-3178161 |
| Chinese Name | Marizomib |
| Synonyms | MARIZOMIB; NPI-0052; UNII-703P9YDP7F |
| Molecular Formula | C15H20ClNO4 |
| Molecular Weight | 313.78 |
| Purity | ≥95 (HPLC) |
| Appearance | powder |
| Storage Condition | -20°C, sealed, dry |
| Application | Marizomib (Salinosporamide A) is a second-generation, irreversible, brain-penetrating pan-proteasome inhibitor. Marizomib inhibits the CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2 |
| SMILES | ClCC[C@@H]1[C@@]2(OC(=O)[C@@]2(NC1=O)[C@@H](O)[C@H]3CCCC=C3)C |
| InChI | 1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)/t9-,10+,11+,14+,15+/m1/s1 |
| InChI Key | NGWSFRIPKNWYAO-SHTIJGAHSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/178794_1_437742_34_2.pdf |
| Transport Info | Product name: Salinamycin A (NPI-0052) |
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