CAS Number867160-71-2
Synonymscis-3-[8-amino-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI-906 (Linsitinib); Kinome_3532; cis-3-(8-amino-1-(2-phenyl-7-quinolinyl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol; Linsitinib; cis-3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-1-yl]-1-methylcyclobutan-1-ol; OSI906; cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI-906AA; OSI-906
Molecular FormulaC26H23O1N5
Molecular Weight421.5
Density1.4±0.1 g/cm3
AppearanceWhite to yellow solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 867160-71-2 |
| Catalog No. | 2A-3178162 |
| Chinese Name | Linsitinib |
| Synonyms | cis-3-[8-amino-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI-906 (Linsitinib); Kinome_3532; cis-3-(8-amino-1-(2-phenyl-7-quinolinyl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol; Linsitinib; cis-3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-1-yl]-1-methylcyclobutan-1-ol; OSI906; cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI-906AA; OSI-906 |
| Molecular Formula | C26H23O1N5 |
| Molecular Weight | 421.5 |
| Density | 1.4±0.1 g/cm3 |
| Appearance | White to yellow solid |
| Storage Condition | -20℃ |
| Application | Losmapimod is a dual inhibitor of IGF-1 and insulin receptors with IC50s of 35 and 75 nM respectively. |
| MDL Number | MFCD12912153 |
| SMILES | CC1(O)CC(c2nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c3c(N)nccn23)C1 |
| InChI Key | PKCDDUHJAFVJJB-UHFFFAOYSA-N |
| MSDS | msds/178795_1_867160_71_2.pdf |
| Transport Info | Product Name: OSI-906(Linsitinib) |
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