CAS Number1239262-52-2
SynonymsTUBASTATIN A HYDROCHLORIDE; N-hydroxy-4-({2-methyl-1H,3H,4H-pyrido[4,3-b]indol-5-yl}methyl)benzamide hydrochloride; N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide; Tubastatin A Trifluoroacetic Acid Salt; TUBASTSTINA HCL; TUBASTATIN A ((2-METHYL-3,4-DIHYDRO-1H-PYRIDO[4,3-B]-INDOL- 5(2H)-YL)METHYL)BENZAMIDE); TUBASTATIN A_HCL; Tubastatin A; TUBASTANTIN A; Tubastatin A (trifluoroacetate salt); TRIETHYLENETHIOPHOSPHORAMIDE,WHITE SOLID; [4-({2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl}methyl)phenyl]formamido 2,2,2-trifluoroacetate; N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5 -yl)methyl]benzamide; N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide
Molecular FormulaC22H22F3N3O4
Molecular Weight371.86
Purity≥98 (HPLC)%
Density1.3±0.1 g/cm3
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1239262-52-2 |
| Catalog No. | 2A-3178167 |
| Chinese Name | N-羟基-4-[(1,2,3,4-四氢-2-甲基-5H-吡啶并[4,3-b]吲哚-5-基)甲基]苯甲酰胺 2,2,2-三氟乙酸酯 |
| Synonyms | TUBASTATIN A HYDROCHLORIDE; N-hydroxy-4-({2-methyl-1H,3H,4H-pyrido[4,3-b]indol-5-yl}methyl)benzamide hydrochloride; N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide; Tubastatin A Trifluoroacetic Acid Salt; TUBASTSTINA HCL; TUBASTATIN A ((2-METHYL-3,4-DIHYDRO-1H-PYRIDO[4,3-B]-INDOL- 5(2H)-YL)METHYL)BENZAMIDE); TUBASTATIN A_HCL; Tubastatin A; TUBASTANTIN A; Tubastatin A (trifluoroacetate salt); TRIETHYLENETHIOPHOSPHORAMIDE,WHITE SOLID; [4-({2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl}methyl)phenyl]formamido 2,2,2-trifluoroacetate; N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5 -yl)methyl]benzamide; N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide |
| Molecular Formula | C22H22F3N3O4 |
| Molecular Weight | 371.86 |
| Purity | ≥98 (HPLC) |
| Density | 1.3±0.1 g/cm3 |
| Appearance | powder |
| Storage Condition | room temperature |
| Application | Tubastatin A (TSA) TFA is a potent, selective inhibitor of HDAC6 with an IC50 of 15 nM and is over 1000-fold selective for isoforms other than HDAC8. Tubastatin A TFA also inhibits HDAC10 and MBLAC2. |
| PubChem ID | 329825114 |
| MDL Number | MFCD20488052 |
| SMILES | O=C(NO)C1=CC=C(CN2C3=C(C=CC=C3)C4=C2CCN(C)C4)C=C1.Cl |
| InChI | 1S/C20H21N3O2.ClH/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25;/h2-9,25H,10-13H2,1H3,(H,21,24);1H |
| InChI Key | LJTSJTWIMOGKRJ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/178800_1_1239262_52_2.pdf |
| Transport Info | Product Name: Tobastatin Hydrochloride A |
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