CAS Number81-64-1
SynonymsMFCD00001209; EINECS 201-368-7; 1,4-hydroxyanthraquinone; QUINIZARINE; DSD ACID; smokeoranger; 1,4-Dihydroxy-9,10-anthraquinone; Quinizarin; Chinizarin; 1,4-Dihydroxy-9,10-anthracene-dione; 1,4-Dihydroxyanthraquinone; Quinizalin; QUINAZARIN; 1,4-Doa; 1,4-dihydroxyanthracene-9,10-dione; quiniazarine
Molecular FormulaC14H8O4
Molecular Weight240.21
Purity≥97.0 (acidimetric)%
Density1.5±0.1 g/cm3
Boiling Point450 °C/1013 hPa
Melting Point195-198 °C
Appearancepowder
Symbol
Signal WordWarning
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 81-64-1 |
| Catalog No. | 2A-9017353 |
| Chinese Name | 1,4-二羟基蒽醌 |
| Synonyms | MFCD00001209; EINECS 201-368-7; 1,4-hydroxyanthraquinone; QUINIZARINE; DSD ACID; smokeoranger; 1,4-Dihydroxy-9,10-anthraquinone; Quinizarin; Chinizarin; 1,4-Dihydroxy-9,10-anthracene-dione; 1,4-Dihydroxyanthraquinone; Quinizalin; QUINAZARIN; 1,4-Doa; 1,4-dihydroxyanthracene-9,10-dione; quiniazarine |
| Molecular Formula | C14H8O4 |
| Molecular Weight | 240.21 |
| Purity | ≥97.0 (acidimetric) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 450 °C/1013 hPa |
| Melting Point | 195-198 °C |
| Appearance | powder |
| Water Solubility | <1 g/L (20 ºC) |
| Storage Condition | Store sealed in a cool place. Packed in iron drums |
| Packaging | II; III |
| Application | Quinizarin (1,4-Dihydroxyanthraquinone) is part of anticancer drugs such as Doxorubicin, Daunorubicin, Adriamycin, etc., and interacts with DNA through insertion (Kd=86.1 μM). Quinizarin is a fungicid |
| HTC | 2914610000 |
| MDL Number | MFCD00001209 |
| SMILES | Oc1c2c(c(cc1)O)C(=O)c3c(cccc3)C2=O |
| InChI | 1S/C14H8O4/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-6,15-16H |
| InChI Key | GUEIZVNYDFNHJU-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352115 |
| Hazard Symbols | 4.1 |
| MSDS | msds/17353_1_81_64_1.pdf |
| Bioactivity | Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Fungal In Vitro 1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped cellulose (CL) (denoted as 1,4-DHAQ@CL) microporous nanofiber film has been achieved via simple electrospinning and subsequent deacetylating, and used for highly sensitive and selective fluorescence detection of Cu(2+) in aqueous solution[1]. References [1]. Verebová V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444(1):50-55. [2]. Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin. [3]. Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46(1):367-373. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 465.3±40.0 °C at 760 mmHg Melting Point 198-199 °C(lit.) Molecular Formula C14H8O4 Molecular Weight 240.211 Flash Point 249.3±23.8 °C Exact Mass 240.042252 PSA 74.60000 LogP 4.47 Vapour density 8.3 (vs air) Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.733 InChIKey GUEIZVNYDFNHJU-UHFFFAOYSA-N SMILES O=C1c2ccccc2C(=O)c2c(O)ccc(O)c21 Water Solubility <1 g/L (20 ºC) |
| Use of | Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2]. Properties Articles35 Name quinizarin Synonym More Synonyms Quinizarin Biological Activity Description Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Fungal In Vitro 1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped cellulose (CL) (denoted as 1,4-DHAQ@CL) microporous nanofiber film has been achieved via simple electrospinning and subsequent deacetylating, and used for highly sensitive and selective fluorescence detection of Cu(2+) in aqueous solution[1]. References [1]. Verebová V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444(1):50-55. [2]. Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin. [3]. Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46(1):367-373. Chemical & Physical Properties Molecular Formula C14H8O4 Exact Mass 240.042252 PSA 74.60000 Vapour density 8.3 (vs air) Index of Refraction 1.733 InChIKey GUEIZVNYDFNHJU-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 3077 International Maritime Transport Danger Regulations: 3077 International Air Transport Danger Regulations: 3077 14.2 United Nations shipping name European land transport hazard regulations: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1,4- Dihydroxyanthraquinone) IMDG Code: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1,4- Dihydroxyanthraquinone) International air transport hazard regulations: Environmentally hazardous substance, solid, n.o.s. (1,4-Dihydroxyanthraquinone) 14.3 Transport hazard categories European land transport Dangerous Regulations: 9 International sea transport Dangerous Regulations: 9 International air transport Dangerous Regulations: 9 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: Yes International Maritime Transport Dangerous Regulations International Air Transport Dangerous Regulations: Yes Marine Pollutants (Yes/No): Yes 14.6 Special reminder to users further information Dangerous goods are individually packaged, with liquids exceeding 5 liters or solids exceeding 5 kilograms. The outer packaging of each independent package and the combined independent inner package must have EHS on it. Identification (according to European ADR Regulation 2.2.9.1.10, IMDG Regulation 2.10.3), See reverse side of invoice or packing slip. |
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