MP-412

Name: MP-412
Brand: 2A Biotech
SKU: 2A-1170974

CAS Number451492-95-8

SynonymsHMS3244N15; UNII-41OXH4FE7B; RS0030; AV-412 free base; AV412(Free base); AV-412 (free base)

Molecular FormulaC27H28ClFN6O

Molecular Weight507.002

Purity98%%

Density1.3±0.1 g/cm3

Boiling Point672.9±55.0 °C at 760 mmHg

Cat. No.: 2A-1170974 Purity: 98%%

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Quality Control of [ 451492-95-8 ] Purity: 98%% SDS Specification MoL

Chemical & Physical Properties
CAS Number	451492-95-8
Catalog No.	2A-1170974
Chinese Name	AV-412自由基
Synonyms	HMS3244N15; UNII-41OXH4FE7B; RS0030; AV-412 free base; AV412(Free base); AV-412 (free base)
Molecular Formula	C27H28ClFN6O
Molecular Weight	507.002
Purity	98%
Density	1.3±0.1 g/cm3
Boiling Point	672.9±55.0 °C at 760 mmHg
Storage Condition	2-8℃
Application	AV-412 (MP412) is an EGFR inhibitor. The IC50 values for inhibiting EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2 are 0.75, 0.5, 0.79, 2.3, and 19 nM respectively.
PubChem ID	14762362
SMILES	C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1C#CC(C)(C)N1CCN(C)CC1
InChI	InChI=1S/C27H28ClFN6O/c1-5-25(36)33-23-16-20-24(30-17-31-26(20)32-19-6-7-22(29)21(28)15-19)14-18(23)8-9-27(2,3)35-12-10-34(4)11-13-35/h5-7,14-17H,1,10-13H2,2-4H3,(H,33,36)(H,30,31,32)
InChI Key	ZAJXXUDARPGGOC-UHFFFAOYSA-N
Transport Info	Product name: AV 412

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