EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > AZD 3759
AZD 3759 structure, CAS 1626387-80-1

AZD 3759

CAS Number1626387-80-1

Synonyms(R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate; AZD-3759

Molecular FormulaC22H23ClFN5O3

Molecular Weight459.901

Purity98%%

Density1.4±0.1 g/cm3

Boiling Point571.4±50.0 °C at 760 mmHg

Melting Point192.4 °C(醇、酯), 193.3 °C (水)

Flash Point

AppearanceWhite or off-white solid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-1170973 Purity: 98%%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 1626387-80-1 ] Purity: 98%% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1626387-80-1
Catalog No.2A-1170973
Chinese NameAZD-3759
Synonyms(R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate; AZD-3759
Molecular FormulaC22H23ClFN5O3
Molecular Weight459.901
Purity98%
Density1.4±0.1 g/cm3
Boiling Point571.4±50.0 °C at 760 mmHg
Melting Point192.4 °C(醇、酯), 193.3 °C (水)
AppearanceWhite or off-white solid
Water SolubilityDissolve in DMSO
Storage Condition-20℃
ApplicationAZD3759 is a potent CNS-permeable EGFR inhibitor. For EGFRwt, EGFRL858R and EGFRexon 19Del, the IC50 is 0.3, 0.2 and 0.2 nM respectively.
PubChem ID207761305
SMILESCOc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC(=O)N1CCN(C)CC1C
InChIInChI=1S/C22H23ClFN5O3/c1-13-11-28(2)7-8-29(13)22(30)32-19-9-14-17(10-18(19)31-3)25-12-26-21(14)27-16-6-4-5-15(23)20(16)24/h4-6,9-10,12-13H,7-8,11H2,1-3H3,(H,25,26,27)/t13-/m1/s1
InChI KeyMXDSJQHFFDGFDK-CYBMUJFWSA-N
Transport InfoProduct name: AZD3759
Related Products in Specialty Chemicals
1-(4-(5-(5-amino-6-(5-(tert-butyl)-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1H-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one1620576-64-82A-1170967
IMISOPASEM MANGANESE218791-21-02A-1170969
MDL 72274A85278-24-62A-1170970
RSM932A850807-63-52A-1170971
GDC-0810(ARN-810)1365888-06-72A-1170972
MP-412451492-95-82A-1170974
1H-Pyrazolo[3,4-b]pyridin-4-ol, 1-[(4-Methoxyphenyl)Methyl]-924909-16-02A-1170976
PD 0332991 HCl827022-32-22A-1170977
PACRITINIB937272-79-22A-1170978
IDO inhibitor 11204669-37-32A-1170979
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA