
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 928037-13-2 |
| Catalog No. | 2A-1170933 |
| Chinese Name | N-[2-氟-4-[[2-[[[4-(4-甲基哌嗪-1-基)哌啶-1-基]羰基]氨基]吡啶-4-基]氧基]苯基]-N'-(4-氟苯基)环丙烷-1,1-二甲酰胺 |
| Synonyms | Golvatinib; Golvatinib (USAN); UNII-516Z3YP58E; E7050; cc-653; E-7050 |
| Molecular Formula | C33H37F2N7O4 |
| Molecular Weight | 633.688 |
| Purity | 98% |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 867.5±65.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | E-7050 is a dual inhibitor of c-Met and VEGFR2 with IC50 values of 14 and 16 nM respectively. |
| PubChem ID | 24765550 |
| SMILES | CN1CCN(C2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)C5(C(=O)Nc6ccc(F)cc6)CC5)c(F)c4)ccn3)CC2)CC1 |
| InChI | InChI=1S/C33H37F2N7O4/c1-40-16-18-41(19-17-40)24-9-14-42(15-10-24)32(45)39-29-21-26(8-13-36-29)46-25-6-7-28(27(35)20-25)38-31(44)33(11-12-33)30(43)37-23-4-2-22(34)3-5-23/h2-8,13,20-21,24H,9-12,14-19H2,1H3,(H,37,43)(H,38,44)(H,36,39,45) |
| InChI Key | UQRCJCNVNUFYDX-UHFFFAOYSA-N |
| Transport Info | Product Name: Golvatinib (E7050) |
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| PD0332991 Isethionate | 827022-33-3 | 2A-1170936 |
| LY2835219 | 1231930-82-7 | 2A-1170938 |
| SU 5416 | 204005-46-9 | 2A-1170940 |
| LEE011 | 1211441-98-3 | 2A-1170941 |
| Browse all Specialty Chemicals products » | ||
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