OSI-027

Name: OSI-027
Brand: 2A Biotech
SKU: 2A-1170401

CAS Number936890-98-1

SynonymsK1146_Kinasechem; cc-501; OSI-027; S2624_Selleck

Molecular FormulaC21H22N6O3

Molecular Weight406.438

Density1.6±0.1 g/cm3

Boiling Point591.4±60.0 °C at 760 mmHg

Appearancepowder

Cat. No.: 2A-1170401 Purity:

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Quality Control of [ 936890-98-1 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	936890-98-1
Catalog No.	2A-1170401
Chinese Name	OSI-027
Synonyms	K1146_Kinasechem; cc-501; OSI-027; S2624_Selleck
Molecular Formula	C21H22N6O3
Molecular Weight	406.438
Density	1.6±0.1 g/cm3
Boiling Point	591.4±60.0 °C at 760 mmHg
Appearance	powder
Storage Condition	-20℃
Application	OSI-027 is an ATP-competitive inhibitor of mTOR kinase activity with an IC50 of 4 nM. OSI-027 inhibits mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.
PubChem ID	123055425
SMILES	COc1cccc2cc(-c3nc(C4CCC(C(=O)O)CC4)n4ncnc(N)c34)[nH]c12
InChI	InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24)
InChI Key	JROFGZPOBKIAEW-UHFFFAOYSA-N
Transport Info	Product name: OSI-027

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