
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 601514-19-6 |
| Catalog No. | 2A-1170406 |
| Chinese Name | 3-[[6-(3-氨基苯基)-7H-吡咯并[2,3-d]嘧啶-4-基]氧基]苯酚 |
| Synonyms | 3-{[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy}phenol; TWS 119; Neurogenesis Inducer; TWS119 |
| Molecular Formula | C18H14N4O2 |
| Molecular Weight | 318.329 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 646.0±55.0 °C at 760 mmHg |
| Appearance | light yellow solid |
| Storage Condition | Desiccate at +4°C |
| Application | TWS119 is a GSK-3β specific inhibitor with an IC50 value of 30 nM and can activate the wnt/β-catenin signaling pathway. |
| PubChem ID | 14720344 |
| SMILES | Nc1cccc(-c2cc3c(Oc4cccc(O)c4)ncnc3[nH]2)c1 |
| InChI | InChI=1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22) |
| InChI Key | VPVLEBIVXZSOMQ-UHFFFAOYSA-N |
| Transport Info | Product name: TWS119 |
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