
CAS Number690206-97-4
SynonymsN-(4-Chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine; N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine; Anilinoquinazoline deriv. 4; ZM-306416; ZM306416; ZM 306416
Molecular FormulaC16H13ClFN3O2
Molecular Weight333.745
Density1.4±0.1 g/cm3
Boiling Point434.1±45.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 690206-97-4 |
| Catalog No. | 2A-1170396 |
| Chinese Name | N-(4-氯-2-氟苯基)-6,7-二甲氧基-4-喹唑啉胺 |
| Synonyms | N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine; N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine; Anilinoquinazoline deriv. 4; ZM-306416; ZM306416; ZM 306416 |
| Molecular Formula | C16H13ClFN3O2 |
| Molecular Weight | 333.745 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 434.1±45.0 °C at 760 mmHg |
| Storage Condition | Desiccate at RT |
| Application | ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50 values of 0.1 and 2 μM for KDR and Flt, respectively. ZM-306416 is also an inhibitor of EGFR with an IC50 value of less than 10 nM. |
| PubChem ID | 8034284 |
| SMILES | COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC |
| InChI | InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21) |
| InChI Key | YHUIUSRCUKUUQA-UHFFFAOYSA-N |
| Transport Info | Product name: ZM 306416 |
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