Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea

3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea

Name: 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea
Brand: 2A Biotech
SKU: 2A-1170307

CAS Number872511-34-7

SynonymsBGJ-398; BGJ398; infigratinib; NVP-BGJ398

Molecular FormulaC26H31Cl2N7O3

Molecular Weight560.475

Density1.4±0.1 g/cm3

Boiling Point747.9±60.0 °C at 760 mmHg

MSDSChinese English

Cat. No.: 2A-1170307 Purity:

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Quality Control of [ 872511-34-7 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	872511-34-7
Catalog No.	2A-1170307
Chinese Name	Infigratinib (BGJ398)
Synonyms	BGJ-398; BGJ398; infigratinib; NVP-BGJ398
Molecular Formula	C26H31Cl2N7O3
Molecular Weight	560.475
Density	1.4±0.1 g/cm3
Boiling Point	747.9±60.0 °C at 760 mmHg
Storage Condition	-20°C
Application	Infigratinib (BGJ-398) is a potent inhibitor of the FGFR family, with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for inhibiting FGFR1, FGFR2, FGFR3, and FGFR4 respectively.
PubChem ID	124359248
InChI	InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)
InChI Key	QADPYRIHXKWUSV-UHFFFAOYSA-N
Transport Info	Product name: BGJ398 (NVP-BGJ398)

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3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea

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