
CAS Number1194961-19-7
Synonyms2-{[(1R,2S)-2-Aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-5-pyrimidinecarboxamide; PRT318; 2-(((1R,2S)-2-aminocyclohexyl)amino)-4-(m-tolylamino)pyrimidine-5-carboxamide; P142-76; PRT 060318
Molecular FormulaC18H24N6O
Molecular Weight340.423
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point602.1±65.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1194961-19-7 |
| Catalog No. | 2A-1170309 |
| Chinese Name | PRT-060318 |
| Synonyms | 2-{[(1R,2S)-2-Aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-5-pyrimidinecarboxamide; PRT318; 2-(((1R,2S)-2-aminocyclohexyl)amino)-4-(m-tolylamino)pyrimidine-5-carboxamide; P142-76; PRT 060318 |
| Molecular Formula | C18H24N6O |
| Molecular Weight | 340.423 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 602.1±65.0 °C at 760 mmHg |
| Application | PRT-060318 (PRT318) is a novel and selective tyrosine kinase (Syk) inhibitor with an IC50 value of 4 nM. |
| PubChem ID | 16595768 |
| SMILES | Cc1cccc(Nc2nc(NC3CCCCC3N)ncc2C(N)=O)c1 |
| InChI | InChI=1S/C18H24N6O/c1-11-5-4-6-12(9-11)22-17-13(16(20)25)10-21-18(24-17)23-15-8-3-2-7-14(15)19/h4-6,9-10,14-15H,2-3,7-8,19H2,1H3,(H2,20,25)(H2,21,22,23,24)/t14-,15+/m0/s1 |
| InChI Key | NZNTWOVDIXCHHS-LSDHHAIUSA-N |
| Transport Info | Product name: PRT 060318 |
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