CAS Number1009298-09-2
SynonymsAZD-8055; AZD8055; (5-{2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol; [5-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol
Molecular FormulaC25H31N5O4
Molecular Weight465.545
Density1.2±0.1 g/cm3
Boiling Point694.3±65.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1009298-09-2 |
| Catalog No. | 2A-1170301 |
| Chinese Name | AZD8055 |
| Synonyms | AZD-8055; AZD8055; (5-{2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol; [5-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol |
| Molecular Formula | C25H31N5O4 |
| Molecular Weight | 465.545 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 694.3±65.0 °C at 760 mmHg |
| Storage Condition | -20°C |
| Application | AZD-8055 is an ATP-competitive mTOR inhibitor with an IC50 of 0.8 nM. AZD-8055 inhibits mTORC1 and mTORC2. |
| PubChem ID | 58097209 |
| SMILES | COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1CO |
| InChI | InChI=1S/C25H31N5O4/c1-16-14-33-10-8-29(16)24-20-5-6-21(18-4-7-22(32-3)19(12-18)13-31)26-23(20)27-25(28-24)30-9-11-34-15-17(30)2/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17-/m0/s1 |
| InChI Key | KVLFRAWTRWDEDF-IRXDYDNUSA-N |
| Transport Info | Product name: AZD8055 |
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