| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1173204-81-3 |
| Catalog No. | 2A-1170296 |
| Chinese Name | 1-[4-[3-乙基-7-(吗啉-4-基)-3H-[1,2,3]三唑并[4,5-d]嘧啶-5-基]苯基]-3-[4-[(4-甲基哌嗪-1-基)羰基]苯基]脲 |
| Synonyms | PKI-402; pound not PKI402 pound not PKI 402 |
| Molecular Formula | C29H34N10O3 |
| Molecular Weight | 570.646 |
| Density | 1.4±0.1 g/cm3 |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | PKI-402 is a potent PI3K and mTOR inhibitor, inhibiting PI3Kα, mTOR, PI3Kβ, PI3Kδ and PI3Kγ with IC50 of 2, 3, 7, 14 and 16 nM respectively. |
| PubChem ID | 85183600 |
| SMILES | CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)N5CCN(C)CC5)cc4)cc3)nc21 |
| InChI | InChI=1S/C29H34N10O3/c1-3-39-27-24(34-35-39)26(37-16-18-42-19-17-37)32-25(33-27)20-4-8-22(9-5-20)30-29(41)31-23-10-6-21(7-11-23)28(40)38-14-12-36(2)13-15-38/h4-11H,3,12-19H2,1-2H3,(H2,30,31,41) |
| InChI Key | ZAXFYGBKZSQBIV-UHFFFAOYSA-N |
| Transport Info | Product name: PKI-402 |
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