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PP242

Name: PP242
Brand: 2A Biotech
SKU: 2A-1170294

CAS Number1092351-67-1

SynonymsEX-7207; PP-242; 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol; UNII-H5669VNZ7V; QCR-154; CS-0247; 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol; PP 242; 2-(4-Amino-1-isopropyl-1H-pyrazolo(3,4-d)pyrimidin-3-yl)-1H-indol-5-ol; TORKinib; PP242

Molecular FormulaC16H16N6O

Molecular Weight308.338

Density1.6±0.1 g/cm3

Boiling Point642.0±50.0 °C at 760 mmHg

MSDSChinese English

Cat. No.: 2A-1170294 Purity:

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Quality Control of [ 1092351-67-1 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1092351-67-1
Catalog No.	2A-1170294
Chinese Name	Torkinib (PP242)
Synonyms	EX-7207; PP-242; 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol; UNII-H5669VNZ7V; QCR-154; CS-0247; 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol; PP 242; 2-(4-Amino-1-isopropyl-1H-pyrazolo(3,4-d)pyrimidin-3-yl)-1H-indol-5-ol; TORKinib; PP242
Molecular Formula	C16H16N6O
Molecular Weight	308.338
Density	1.6±0.1 g/cm3
Boiling Point	642.0±50.0 °C at 760 mmHg
Storage Condition	Room temperature, dry, sealed
Application	Torkinib (PP 242) is a selective, ATP-competitive mTOR inhibitor with an IC50 of 8 nM. PP242 inhibits mTORC1 and mTORC2 with IC50s of 30 nM and 58 nM, respectively.
PubChem ID	53799230
SMILES	CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21
InChI	InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,20,23H,1-2H3,(H2,17,18,19)
InChI Key	MFAQYJIYDMLAIM-UHFFFAOYSA-N
Transport Info	Product name: PP242

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PP242

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