PF-05212384

Name: PF-05212384
Brand: 2A Biotech
SKU: 2A-1170290

CAS Number1197160-78-3

SynonymsPF-05212384 (PKI-587); PKI 587; cc-54; Gedatolisib; PF 05212384; PKI-587; S2628_Selleck

Molecular FormulaC32H41N9O4

Molecular Weight615.726

Density1.4±0.1 g/cm3

Cat. No.: 2A-1170290 Purity:

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Quality Control of [ 1197160-78-3 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1197160-78-3
Catalog No.	2A-1170290
Chinese Name	吉达利塞
Synonyms	PF-05212384 (PKI-587); PKI 587; cc-54; Gedatolisib; PF 05212384; PKI-587; S2628_Selleck
Molecular Formula	C32H41N9O4
Molecular Weight	615.726
Density	1.4±0.1 g/cm3
Storage Condition	2~8°C
Application	Gedatolisib (PKI-587) is a highly potent dual PI3Kα, PI3Kγ and mTOR inhibitor with IC50 of 0.4 nM, 5.4 nM and 1.6 nM respectively. PKI-587 is equally effective in the mTOR complexes mTORC1 and mTORC2.
HTC	29349990
PubChem ID	85851771
SMILES	CN(C)C1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(-c4nc(N5CCOCC5)nc(N5CCOCC5)n4)cc3)cc2)CC1
InChI	InChI=1S/C32H41N9O4/c1-38(2)27-11-13-39(14-12-27)29(42)24-5-9-26(10-6-24)34-32(43)33-25-7-3-23(4-8-25)28-35-30(40-15-19-44-20-16-40)37-31(36-28)41-17-21-45-22-18-41/h3-10,27H,11-22H2,1-2H3,(H2,33,34,43)
InChI Key	DWZAEMINVBZMHQ-UHFFFAOYSA-N
Transport Info	Product name: Gedatolisib (PF-05212384, PKI-587)

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