CAS Number71-44-3
SynonymsSpermin; MUSCULAMINE HYDROCHLORIDE; EINECS 200-754-2; N,N'-Bis(3-aminopropyl)butane-1,4-diamine; N,N'-Bis(3-aminopropyl)-1,4-butanediamine; N,N'-Bis(3-aminopropyl)butan-1,4-diamin; N,N'-Bis(3-aminopropyl)-1,4-diaminobutane; N,N'-Bis(3-aminopropyl)tetramethylenediamine; Spermine; SPERMINE HYDROCHLORIDE; MFCD00012914; 1,5,10,14-Tetraazatetradecane; NEURIDINE HYDROCHLORIDE; N1,N4-bis(3-aminopropyl)-1,4-butanediamine
Molecular FormulaNH2(CH2)3NH(CH2)4NH(CH2)3NH2
Molecular Weight202.34
Purity≥97%
Density0.9±0.1 g/cm3
Boiling Point150 °C/5 mmHg (lit.)
Melting Point28-30 (lit.)
AppearanceWhite to slightly off-white powder crystal
EINECS200-754-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 71-44-3 |
| Catalog No. | 2A-9017018 |
| Chinese Name | 精胺 |
| Synonyms | Spermin; MUSCULAMINE HYDROCHLORIDE; EINECS 200-754-2; N,N'-Bis(3-aminopropyl)butane-1,4-diamine; N,N'-Bis(3-aminopropyl)-1,4-butanediamine; N,N'-Bis(3-aminopropyl)butan-1,4-diamin; N,N'-Bis(3-aminopropyl)-1,4-diaminobutane; N,N'-Bis(3-aminopropyl)tetramethylenediamine; Spermine; SPERMINE HYDROCHLORIDE; MFCD00012914; 1,5,10,14-Tetraazatetradecane; NEURIDINE HYDROCHLORIDE; N1,N4-bis(3-aminopropyl)-1,4-butanediamine |
| Molecular Formula | NH2(CH2)3NH(CH2)4NH(CH2)3NH2 |
| Molecular Weight | 202.34 |
| Purity | ≥97 |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 150 °C/5 mmHg (lit.) |
| Melting Point | 28-30 (lit.) |
| Appearance | White to slightly off-white powder crystal |
| Water Solubility | H2O: 1 M at 20 °C, clear, colorless |
| Storage Condition | Storage temperature 4ºC |
| Packaging | III |
| Application | Spermine acts as a direct free radical scavenger, protecting DNA from free radical attack. |
| EINECS | 200-754-2 |
| HTC | 2929909090 |
| PubChem ID | 24899550 |
| MDL Number | MFCD00008215 |
| SMILES | [H]N(CCCN)CCCCN([H])CCCN |
| InChI | 1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2 |
| InChI Key | PFNFFQXMRSDOHW-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1750791 |
| NACRES Code | NA.25 |
| UNSPSC | 12352116 |
| Hazard Symbols | 8 |
| MSDS | msds/17018_1_71_44_3.pdf |
| Bioactivity | Spermine functions directly as a free radical scabenger to protect DNA from free radical attack. Related Catalog Natural Products >> Others Research Areas >> Metabolic Disease Target Human Endogenous Metabolite In Vitro Spermine at physiologically relevant concentrations inhibits ROS-induced DNA damage, with maximal inhibition observed at 1 to 2 mM. These concentrations are well within the estimates for the physiological concentrations of spermine[1]. References [1]. Ha HC, et al. The natural polyamine spermine functions directly as a free radical scavenger. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11140-5. Chemical & Physical Properties Density 0.9±0.1 g/cm3 Boiling Point 308.4±0.0 °C at 760 mmHg Melting Point 310-311 °C (dec.)(lit.) Molecular Formula C10H26N4 Molecular Weight 202.340 Flash Point 175.6±22.6 °C Exact Mass 202.215744 PSA 76.10000 LogP -0.96 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.485 InChIKey PFNFFQXMRSDOHW-UHFFFAOYSA-N SMILES NCCCNCCCCNCCCN Storage condition 2-8°C Water Solubility H2O: 1 M at 20 °C, clear, colorless |
| Use of | Spermine functions directly as a free radical scabenger to protect DNA from free radical attack. Properties Articles155 Name spermine Synonym More Synonyms Spermine Biological Activity Description Spermine functions directly as a free radical scabenger to protect DNA from free radical attack. Related Catalog Natural Products >> Others Research Areas >> Metabolic Disease Human Endogenous Metabolite References [1]. Ha HC, et al. The natural polyamine spermine functions directly as a free radical scavenger. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11140-5. Chemical & Physical Properties Molecular Formula C10H26N4 Exact Mass 202.215744 PSA 76.10000 LogP -0.96 Index of Refraction 1.485 InChIKey PFNFFQXMRSDOHW-UHFFFAOYSA-N SMILES NCCCNCCCCNCCCN |
| Tax Rebate | 9.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 3259 International Dangerous Regulations for sea transport: 3259 International Dangerous Regulations for air transport: 3259 14.2 United Nations shipping name European Land Transport Dangerous Regulations: POLYAMINES, SOLID, CORROSIVE, N.O.S. (4,9-Diazadodecamethylenediamine) IMDG: POLYAMINES, SOLID, CORROSIVE, N.O.S. (4,9-Diazadodecamethylenediamine) International air transport hazard regulations: Polyamines, solid, corrosive, n.o.s. (4,9-Diazadodecamethylenediamine) 14.3 Transport hazard categories European Dangerous Regulations for land transport: 8 International Dangerous Regulations for sea transport: 8 International Dangerous Regulations for air transport: 8 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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