
CAS Number73-03-0
SynonymsAdenine cordyceposide; EINECS 200-791-4; Adenosine,3-deoxy; Cordycepine; MFCD00037998; Cordycepin; Cordyceps fungus powder; cordycepin crystalline; 3'-Deoxyadenosine; (-)-cordycepin; 3'-Deoxy-D-adenosine
Molecular FormulaC10H13N5O3
Molecular Weight491.18
Purity≥95%
Density1.9±0.1 g/cm3
Boiling Point627.2±65.0 °C at 760 mmHg
Melting Point225-229ºC
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 73-03-0 |
| Catalog No. | 2A-9017035 |
| Chinese Name | 虫草素 |
| Synonyms | Adenine cordyceposide; EINECS 200-791-4; Adenosine,3-deoxy; Cordycepine; MFCD00037998; Cordycepin; Cordyceps fungus powder; cordycepin crystalline; 3'-Deoxyadenosine; (-)-cordycepin; 3'-Deoxy-D-adenosine |
| Molecular Formula | C10H13N5O3 |
| Molecular Weight | 491.18 |
| Purity | ≥95 |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 627.2±65.0 °C at 760 mmHg |
| Melting Point | 225-229ºC |
| Appearance | powder |
| Storage Condition | This product should be sealed and stored dry and b |
| Application | Cordycepin, a nucleoside derivative isolated from Cordyceps sinensis, inhibits IL-1β-induced expression of MMP-1 and MMP-3 in rheumatoid arthritis synovial fibroblasts (RASF) in a dose-dependent manne |
| HTC | 29349990 |
| PubChem ID | 24893135 |
| MDL Number | MFCD00057015 |
| SMILES | [Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)CC3O |
| InChI | 1S/C10H16N5O12P3.Na.H/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(16)1-5(25-10)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;/h3-6,10,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);; |
| InChI Key | FRGBONDYLMUOMH-UHFFFAOYSA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| MSDS | msds/17035_1_73_03_0.pdf |
| Use of | Cordycepin, which is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner. Properties Articles65 Name Cordycepin Synonym More Synonyms Cordycepin Biological Activity Description Cordycepin, which is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> MMP Natural Products >> Alkaloid Research Areas >> Cancer Research Areas >> Inflammation/Immunology References [1]. Noh EM, et al. Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. Rheumatology (Oxford). 2009 Jan;48(1):45-8. Chemical & Physical Properties Molecular Formula C10H13N5O3 Exact Mass 251.101837 PSA 119.31000 LogP -0.41 Index of Refraction 1.863 InChIKey OFEZSBMBBKLLBJ-BAJZRUMYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Adenosine, 3'-deoxy- CAS REGISTRY NUMBER : BEILSTEIN REFERENCE NO. : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C10-H13-N5-O3 MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T56 BN DN FN HNJ IZ D- BT5OTJ CQ E1Q HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SEX/DURATION : female 7 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Human HeLa cell DOSE/DURATION : REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 35,119,1982 Safety Information Signal Word Danger Hazard Statements H301-H315-H319-H335 Precautionary Statements P261-P301 + P310-P305 + P351 + P338 Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges Hazard Codes T:Toxic Safety Phrases S26-S45 RIDADR UN 2811 WGK Germany 3 RTECS AU7358610 HS Code 29349990 Precursor & DownStream Precursor 6 CAS#:2627-64-7 2′,3′-Anhydroad... CAS#:116285-72-4 9-[2,5-bis-O-(t... CAS#:71196-28-6 ((2S,4R,5R)-4-a... CAS#:51763-58-7 (2R,3R,5S)-2-(6... DownStream 7 CAS#:4097-22-7 2',3'-Dideoxyad... CAS#:189887-77-2 [(2R,3R,5S)-2-(... CAS#:207347-42-0 N6-Bz-5'-O-DMTr... CAS#:17434-81-0 CORDYCEPIN-5-MO... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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