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Tobramycin Base structure, CAS 32986-56-4

Tobramycin Base

CAS Number32986-56-4

SynonymsTobramaxin; obracin; Tobramycin Base; nebicina; EINECS 251-322-5; Burlamycin; MFCD00077885; Tobracin; tobra; gernebcin; Nebcin; Tobramax; Obramycin; Tobralex; distobram; Tobramycin; Tobrex; nf6

Molecular FormulaC18H37N5O9

Molecular Weight467.51

Purity98%

Density1.5±0.1 g/cm3

Boiling Point775.4±60.0 °C at 760 mmHg

Melting Point178ºC

Flash Point

Appearancepowder

EINECS251-322-5

MSDSChineseEnglish

Symbol6.1

Signal WordWarning

Cat. No.: 2A-9012756 Purity: 98%
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Quality Control of [ 32986-56-4 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number32986-56-4
Catalog No.2A-9012756
Chinese Name妥布霉素
SynonymsTobramaxin; obracin; Tobramycin Base; nebicina; EINECS 251-322-5; Burlamycin; MFCD00077885; Tobracin; tobra; gernebcin; Nebcin; Tobramax; Obramycin; Tobralex; distobram; Tobramycin; Tobrex; nf6
Molecular FormulaC18H37N5O9
Molecular Weight467.51
Purity98
Density1.5±0.1 g/cm3
Boiling Point775.4±60.0 °C at 760 mmHg
Melting Point178ºC
Appearancepowder
Water SolubilityWater solubility: soluble
Storage ConditionStore in inert gas; avoid moisture (moisture absor
PackagingII
ApplicationTobramycin is an aminoglycoside broad-spectrum antibiotic produced by Streptomyces dregs.
EINECS251-322-5
HTC29419090
PubChem ID24900188
MDL NumberMFCD00077885
SMILESNC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
InChI1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
InChI KeyNLVFBUXFDBBNBW-SNGYORCQSA-N
Beilstein/REAXYS1357507
NACRES CodeNA.85
UNSPSC51281626
Hazard Symbols6.1
MSDSmsds/12756_1_32986_56_4.pdf
BioactivityTobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.Target: AntibacterialTobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas [1]. Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA cannot be translated into protein and cell death ensues. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. From Wikipedia [2]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. http://www.toku-e.com/Upload/Products/PDS/20120515001224.pdf [2]. http://en.wikipedia.org/wiki/Tobramycin Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 775.4±60.0 °C at 760 mmHg Melting Point 178ºC Molecular Formula C18H37N5O9 Molecular Weight 467.514 Flash Point 422.8±32.9 °C Exact Mass 467.259125 PSA 268.17000 LogP -3.41 Vapour Pressure 0.0±6.0 mmHg at 25°C Index of Refraction 1.651 InChIKey NLVFBUXFDBBNBW-PBSUHMDJSA-N SMILES NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O
Use ofTobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.Target: AntibacterialTobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas [1]. Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA cannot be translated into protein and cell death ensues. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. From Wikipedia [2]. Properties Articles156 Name tobramycin Synonym More Synonyms Tobramycin Biological Activity Description Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.Target: AntibacterialTobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas [1]. Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA cannot be translated into protein and cell death ensues. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. From Wikipedia [2]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. http://www.toku-e.com/Upload/Products/PDS/20120515001224.pdf [2]. http://en.wikipedia.org/wiki/Tobramycin Chemical & Physical Properties Molecular Formula C18H37N5O9 Exact Mass 467.259125 PSA 268.17000 LogP -3.41 Index of Refraction 1.651 InChIKey NLVFBUXFDBBNBW-PBSUHMDJSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified
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