CAS Number59804-37-4
SynonymsApo-Tenoxicam; 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide; Mobiflex; Tenoxicam; Tenoxicamum; Octiveran; 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide1,1-Dioxide; 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno2,3-e1,2thiazine-3-carboxamide 1,1-dioxide; 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide; 4-Hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide; 2H-thieno2,3-e-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; Tilcotil; 2H-Thieno[2,3-e]-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; Liman; Novo-Tenoxicam
Molecular FormulaC13H11N3O4S2
Molecular Weight337.37
Purity≥98 (perchloric acid titration)%
Density1.7±0.1 g/cm3
Melting Point209-2130ºC
Appearancepowder
Symbol
Signal WordWarning
Please Login or Create an Account to: See VlP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 59804-37-4 |
| Catalog No. | 2A-9012627 |
| Chinese Name | 替诺昔康 |
| Synonyms | Apo-Tenoxicam; 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide; Mobiflex; Tenoxicam; Tenoxicamum; Octiveran; 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide1,1-Dioxide; 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno2,3-e1,2thiazine-3-carboxamide 1,1-dioxide; 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide; 4-Hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide; 2H-thieno2,3-e-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; Tilcotil; 2H-Thieno[2,3-e]-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; Liman; Novo-Tenoxicam |
| Molecular Formula | C13H11N3O4S2 |
| Molecular Weight | 337.37 |
| Purity | ≥98 (perchloric acid titration) |
| Density | 1.7±0.1 g/cm3 |
| Melting Point | 209-2130ºC |
| Appearance | powder |
| Water Solubility | Practically insoluble in water, sparingly soluble |
| Storage Condition | -20°C Freezer |
| Application | Tenoxicam is an anti-inflammatory compound with analgesic and antipyretic activity. |
| HTC | 2934999090 |
| PubChem ID | 24899922 |
| MDL Number | MFCD00083502 |
| SMILES | O=C(NC1=NC=CC=C1)C2=C(O)C(SC=C3)=C3S(N2C)(=O)=O |
| InChI | 1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18) |
| InChI Key | LZNWYQJJBLGYLT-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352202 |
| Hazard Symbols | Transport |
| MSDS | msds/12627_1_59804_37_4.pdf |
| Bioactivity | Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties.Target: COXTenoxicam is a non-steroidal anti-inflammatory drug (NSAID). Tenoxicam-treated patients had significant decrease in nitrite levels (p = 0.036) and XO activity (p = 0.01), but their SOD, GSH-Px enzyme activities, and MDA levels were unchanged from baseline. Tenoxicam may have antioxidant effects, and it may reduce nitrite levels, indicating an alteration of NO pathways [1]. Tenoxicam was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam treatment. Tenoxicam also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia [2]. Related Catalog Research Areas >> Inflammation/Immunology Target COX-1 COX-2 References [1]. Ozgocmen, S., et al., In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis. Ann Clin Lab Sci, 2005. 35(2): p. 137-43. [2]. Galvao, R.I., et al., Tenoxicam exerts a neuroprotective action after cerebral ischemia in rats. Neurochem Res, 2005. 30(1): p. 39-46. Chemical & Physical Properties Density 1.7±0.1 g/cm3 Melting Point 209-2130ºC Molecular Formula C13H11N3O4S2 Molecular Weight 337.374 Exact Mass 337.019104 PSA 136.22000 LogP 1.52 Index of Refraction 1.741 InChIKey LZNWYQJJBLGYLT-UHFFFAOYSA-N SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O Storage condition -20°C Freezer Water Solubility Practically insoluble in water, sparingly soluble in methylene chloride, very slightly soluble in anhydrous ethanol. It dissolves in solutions of acids and alkalis. |
| Use of | Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties.Target: COXTenoxicam is a non-steroidal anti-inflammatory drug (NSAID). Tenoxicam-treated patients had significant decrease in nitrite levels (p = 0.036) and XO activity (p = 0.01), but their SOD, GSH-Px enzyme activities, and MDA levels were unchanged from baseline. Tenoxicam may have antioxidant effects, and it may reduce nitrite levels, indicating an alteration of NO pathways [1]. Tenoxicam was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam treatment. Tenoxicam also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia [2]. Properties Articles36 Name tenoxicam Synonym More Synonyms Tenoxicam Biological Activity Description Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties.Target: COXTenoxicam is a non-steroidal anti-inflammatory drug (NSAID). Tenoxicam-treated patients had significant decrease in nitrite levels (p = 0.036) and XO activity (p = 0.01), but their SOD, GSH-Px enzyme activities, and MDA levels were unchanged from baseline. Tenoxicam may have antioxidant effects, and it may reduce nitrite levels, indicating an alteration of NO pathways [1]. Tenoxicam was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam treatment. Tenoxicam also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia [2]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. Ozgocmen, S., et al., In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis. Ann Clin Lab Sci, 2005. 35(2): p. 137-43. [2]. Galvao, R.I., et al., Tenoxicam exerts a neuroprotective action after cerebral ischemia in rats. Neurochem Res, 2005. 30(1): p. 39-46. Chemical & Physical Properties Molecular Formula C13H11N3O4S2 Exact Mass 337.019104 PSA 136.22000 Index of Refraction 1.741 InChIKey LZNWYQJJBLGYLT-UHFFFAOYSA-N Water Solubility Practically insoluble in water, sparingly soluble in methylene chloride, very slightly soluble in anhydrous ethanol. It dissolves in solutions of acids and alkalis. |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (Tenoxicam) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Tenoxicam) International air transport hazard regulations: Toxic solid, organic, n.o.s. (Tenoxicam) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Temozolomide | 85622-93-1 | 2A-9012620 |
| Temurtide | 66112-59-2 | 2A-9012621 |
| Tenatoprazole | 113712-98-4 | 2A-9012622 |
| Tenidap | 120210-48-2 | 2A-9012623 |
| Teniposide | 29767-20-2 | 2A-9012624 |
| Teopranitol | 81792-35-0 | 2A-9012628 |
| Tepraloxydim | 149979-41-9 | 2A-9012629 |
| Teprenone | 6809-52-5 | 2A-9012630 |
| Terallethrin | 15589-31-8 | 2A-9012632 |
| Terbinafine | 91161-71-6 | 2A-9012636 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS