CAS Number87269-97-4
SynonymsRamiprilate [French]; Ramiprilate; 2-[N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl]-(1S,3S,5S)-2-azabicyclo[3.3.0]octane-3-carboxylic acid; Ramiprilatum; Ramiprilat [INN]; UNII-6N5U4QFC3G; Ramiprilat; Ramiprilatum [Latin]
Molecular FormulaC21H28O5N2
Molecular Weight388.46
Purity98%
Density1.3±0.1 g/cm3
Boiling Point632.2±55.0 °C at 760 mmHg
Melting Point139-141ºC
AppearanceWhite to off-white solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 87269-97-4 |
| Catalog No. | 2A-9012262 |
| Chinese Name | 雷米普利 |
| Synonyms | Ramiprilate [French]; Ramiprilate; 2-[N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl]-(1S,3S,5S)-2-azabicyclo[3.3.0]octane-3-carboxylic acid; Ramiprilatum; Ramiprilat [INN]; UNII-6N5U4QFC3G; Ramiprilat; Ramiprilatum [Latin] |
| Molecular Formula | C21H28O5N2 |
| Molecular Weight | 388.46 |
| Purity | 98 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 632.2±55.0 °C at 760 mmHg |
| Melting Point | 139-141ºC |
| Appearance | White to off-white solid |
| Storage Condition | Refrigerator, Under Inert Atmosphere |
| Application | Ramipril (HOE 498 diacid) is the active metabolite of ramipril and is a potent orally active angiotensin-converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramipril can be used in the study of |
| HTC | 3004909090 |
| MDL Number | MFCD00865787 |
| SMILES | CC(NC(CCc1ccccc1)C(=O)O)C(=O)N1C(C(=O)O)CC2CCCC21 |
| InChI | InChI=1S/C21H28N2O5/c1-13(22-16(20(25)26)11-10-14-6-3-2-4-7-14)19(24)23-17-9-5-8-15(17)12-18(23)21(27)28/h2-4,6-7,13,15-18,22H,5,8-12H2,1H3,(H,25,26)(H,27,28)/t13-,15-,16-,17-,18-/m0/s1 |
| InChI Key | KEDYTOTWMPBSLG-HILJTLORSA-N |
| MSDS | msds/12262_1_87269_97_4.pdf |
| Use of | Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1]. Properties Name Ramiprilat Synonym More Synonyms Ramiprilat Biological Activity Description Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE) Human Endogenous Metabolite References [1]. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1]. Chemical & Physical Properties Molecular Formula C21H28N2O5 Exact Mass 388.199829 PSA 106.94000 Index of Refraction 1.583 InChIKey KEDYTOTWMPBSLG-HILJTLORSA-N Storage condition Refrigerator, Under Inert Atmosphere Safety Information Hazard Codes Xi HS Code 3004909090 Synthetic Route Total: 1 Page CAS#:87333-19-5 Ramiprilat CAS#:87269-97-4 Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 8 p. 865 - 867 Precursor & DownStream Precursor 1 CAS#:87333-19-5 DownStream 0 |
| Transport Info | Product name: (2S,3aS,6aS)-1-((S)-2-(((S)-1-carboxy-3-phenylpropyl)amino)propionyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid |
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