CAS Number59122-46-2
SynonymsMethyl (11α,13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate; MISOPROSTOL ACID; SC 2933; CYTOTEC; Misoprosto; MFCD07772001; Misoprostil; UNII:0E43V0BB57; (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; Misoprostol; methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl}heptanoate; Methyl-7-{(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl}heptanoat; Misogon; DL-MISOPROSTOL
Molecular FormulaC22H38O5
Molecular Weight382.53
Purity≥99 (HPLC)%
Density1.1±0.1 g/cm3
Boiling Point497.3±45.0 °C at 760 mmHg
Melting Point261-263°C
Appearanceliquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 59122-46-2 |
| Catalog No. | 2A-9011464 |
| Chinese Name | 米索前列醇 |
| Synonyms | Methyl (11α,13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate; MISOPROSTOL ACID; SC 2933; CYTOTEC; Misoprosto; MFCD07772001; Misoprostil; UNII:0E43V0BB57; (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; Misoprostol; methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl}heptanoate; Methyl-7-{(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl}heptanoat; Misogon; DL-MISOPROSTOL |
| Molecular Formula | C22H38O5 |
| Molecular Weight | 382.53 |
| Purity | ≥99 (HPLC) |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 497.3±45.0 °C at 760 mmHg |
| Melting Point | 261-263°C |
| Appearance | liquid |
| Storage Condition | −20°C |
| Application | Misoprostol (SC29333) is a prostaglandin E1 (PGE1) analogue that can act on gastric ulcers. |
| PubChem ID | 24897117 |
| MDL Number | MFCD00274550 |
| SMILES | CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC |
| InChI | 1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/m1/s1 |
| InChI Key | OJLOPKGSLYJEMD-URPKTTJQSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352211 |
| Hazard Symbols | 6.1 |
| MSDS | msds/11464_1_59122_46_2.pdf |
| Bioactivity | Misoprostol(SC29333) is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.Target: Prostaglandin ReceptorMisoprostol is a synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties. Misoprostol seems to inhibit gastric acid secretion by a direct action on the parietal cells through binding to the prostaglandin receptor. Administration of misoprostol to EP3+/+ and EP3-/- mice showed similar levels of infarct rescue, indicating that misoprostol protection was not mediated through the EP3 receptor. Taken together, these findings suggest a novel function for misoprostol as a protective agent in cerebral ischemia acting via the PGE(2) EP2 and/or EP4 receptors [1, 2]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Endocrinology References [1]. Li, J., et al., Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia. Neurosci Lett, 2008. 438(2): p. 210-5. [2]. http://www.drugbank.ca/drugs/DB00929 Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 497.3±45.0 °C at 760 mmHg Melting Point 261-263°C Molecular Formula C22H38O5 Molecular Weight 382.534 Flash Point 160.4±22.2 °C Exact Mass 382.271912 PSA 83.83000 LogP 2.91 Vapour Pressure 0.0±2.9 mmHg at 25°C Index of Refraction 1.525 InChIKey OJLOPKGSLYJEMD-URPKTTJQSA-N SMILES CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(=O)OC Storage condition −20°C |
| Use of | Misoprostol(SC29333) is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.Target: Prostaglandin ReceptorMisoprostol is a synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties. Misoprostol seems to inhibit gastric acid secretion by a direct action on the parietal cells through binding to the prostaglandin receptor. Administration of misoprostol to EP3+/+ and EP3-/- mice showed similar levels of infarct rescue, indicating that misoprostol protection was not mediated through the EP3 receptor. Taken together, these findings suggest a novel function for misoprostol as a protective agent in cerebral ischemia acting via the PGE(2) EP2 and/or EP4 receptors [1, 2]. Properties Articles94 Name Misoprostol Synonym More Synonyms Misoprostol Biological Activity Description Misoprostol(SC29333) is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.Target: Prostaglandin ReceptorMisoprostol is a synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties. Misoprostol seems to inhibit gastric acid secretion by a direct action on the parietal cells through binding to the prostaglandin receptor. Administration of misoprostol to EP3+/+ and EP3-/- mice showed similar levels of infarct rescue, indicating that misoprostol protection was not mediated through the EP3 receptor. Taken together, these findings suggest a novel function for misoprostol as a protective agent in cerebral ischemia acting via the PGE(2) EP2 and/or EP4 receptors [1, 2]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Endocrinology References [1]. Li, J., et al., Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia. Neurosci Lett, 2008. 438(2): p. 210-5. [2]. http://www.drugbank.ca/drugs/DB00929 Chemical & Physical Properties Molecular Formula C22H38O5 Exact Mass 382.271912 PSA 83.83000 Index of Refraction 1.525 InChIKey OJLOPKGSLYJEMD-URPKTTJQSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 2810 International Maritime Transport Danger Regulations: 2810 International Air Transport Danger Regulations: 2810 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC LIQUID, ORGANIC, N.O.S. (Misoprostol) IMDG: TOXIC LIQUID, ORGANIC, N.O.S. (Misoprostol) International air transport hazard regulations: Toxic liquid, organic, n.o.s. (Misoprostol) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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