CAS Number25905-77-5
SynonymsTS-370; Minaprin diHCl; MINAPRIN DIHYDROCHLORIDE; MINAPRINE HYDROCHLORIDE; MINAPRINE DIHYDROCHLORIDE; minaprin
Molecular FormulaC17H22N4O
Molecular Weight371.31
Purity98%
Density1.156g/cm3
Boiling Point531.2ºC at 760 mmHg
Melting Point122°
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 25905-77-5 |
| Catalog No. | 2A-9011455 |
| Chinese Name | 米那卜林盐酸盐 |
| Synonyms | TS-370; Minaprin diHCl; MINAPRIN DIHYDROCHLORIDE; MINAPRINE HYDROCHLORIDE; MINAPRINE DIHYDROCHLORIDE; minaprin |
| Molecular Formula | C17H22N4O |
| Molecular Weight | 371.31 |
| Purity | 98 |
| Density | 1.156g/cm3 |
| Boiling Point | 531.2ºC at 760 mmHg |
| Melting Point | 122° |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Minaprine is a reversible inhibitor of monoamine oxidase MAO-A. It also has a weak inhibition on acetylcholinesterase and is an antidepressant compound. |
| HTC | 2934999090 |
| MDL Number | C17H24Cl2N4O |
| SMILES | Cc1cc(-c2ccccc2)nnc1NCCN1CCOCC1 |
| InChI | InChI=1S/C17H22N4O.2ClH/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21;;/h2-6,13H,7-12H2,1H3,(H,18,20);2*1H |
| InChI Key | LDMWSLGGVTVJPG-UHFFFAOYSA-N |
| MSDS | msds/11455_1_25905_77_5.pdf |
| Use of | Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression. Properties Articles25 Name minaprine Synonym More Synonyms Minaprine Biological Activity Description Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression. Related Catalog Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease References [1]. Kan JP, et al. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochem Pharmacol. 1986 Mar 15;35(6):973-8. [2]. Contreras JM, et al. Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem. 1999 Feb 25;42(4):730-41. Chemical & Physical Properties Molecular Formula C17H22N4O PSA 50.28000 LogP 3.81100 Index of Refraction 1.595 InChIKey LDMWSLGGVTVJPG-UHFFFAOYSA-N Storage condition -20℃ Safety Information Signal Word Warning Hazard Statements H302 Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves Hazard Codes Xn Risk Phrases 22 Safety Phrases 36 RIDADR NONH for all modes of transport WGK Germany 3 RTECS QE3477830 HS Code 2934999090 Synthetic Route Phenylboronic acid CAS#:98-80-6 CAS#:25905-77-5 Literature: Bulletin de la Societe Chimique de France, , vol. 130, p. 488 - 492 2-Morpholinoeth... CAS#:2038-03-1 3-chloro-4-meth... CAS#:28657-39-8 4-Morpholineeth... CAS#:90746-30-8 CAS#:25905-77-5 Literature: Turck, A.; Ple, N.; Mojovic, L.; Queguiner, G. Bulletin de la Societe Chimique de France, 1993 , vol. 130, p. 488 - 492 3-Methoxy-6-phe... CAS#:4578-42-1 CAS#:25905-77-5 Literature: Bulletin de la Societe Chimique de France, , vol. 130, p. 488 - 492 Precursor & DownStream Precursor 7 CAS#:98-80-6 Phenylboronic acid CAS#:2038-03-1 2-Morpholinoeth... CAS#:28657-39-8 3-chloro-4-meth... CAS#:90746-30-8 4-Morpholineeth... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Milnacipran | 92623-85-3 | 2A-9011449 |
| Milodistim | 137463-76-4 | 2A-9011450 |
| Milrinone | 78415-72-2 | 2A-0200652 |
| Milverine | 75437-14-8 | 2A-9011453 |
| Minalrestat | 129688-50-2 | 2A-9011454 |
| Mindodilol | 70260-53-6 | 2A-9011456 |
| Minodronic acid | 127657-42-5 | 2A-9011458 |
| Minoxidil | 38304-91-5 | 2A-9011459 |
| Minoxidil sulfate | 83701-22-8 | 2A-0200856 |
| Mirimostim | 121547-04-4 | 2A-9011462 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS