CAS Number86347-15-1
Synonyms4-[(a-Methyl)-2,3-dimethylbenzyl]imidazole Monohydrochloride; 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride (1:1); 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1); (±)-4-(a,2,3-Trimethylbenzyl)imidazole Monohydrochloride; 1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1); medetomidine HCl; UNII:BH210P244U; 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Monohydrochloride; Medetomidine (hydrochloride)
Molecular FormulaC13H17ClN2
Molecular Weight236.74
Purity≥95%
Boiling Point381.9ºC at 760 mmHg
Melting Point168-172 °C
Appearancepowder or crystals
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 86347-15-1 |
| Catalog No. | 2A-9011308 |
| Chinese Name | 盐酸美托咪啶 |
| Synonyms | 4-[(a-Methyl)-2,3-dimethylbenzyl]imidazole Monohydrochloride; 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride (1:1); 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1); (±)-4-(a,2,3-Trimethylbenzyl)imidazole Monohydrochloride; 1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1); medetomidine HCl; UNII:BH210P244U; 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Monohydrochloride; Medetomidine (hydrochloride) |
| Molecular Formula | C13H17ClN2 |
| Molecular Weight | 236.74 |
| Purity | ≥95 |
| Boiling Point | 381.9ºC at 760 mmHg |
| Melting Point | 168-172 °C |
| Appearance | powder or crystals |
| Storage Condition | Refrigerator |
| Application | Medetomidine (Domtor) hydrochloride is an α2 adrenergic receptor agonist, with Kis of α2 and α1 adrenergic receptors of 1.08 nM and 1750 nM respectively. |
| HTC | 2942000000 |
| SMILES | CC(C1=C(C(C)=CC=C1)C)C2=CN=CN2.Cl |
| InChI | InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H |
| InChI Key | VPNGEIHDPSLNMU-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352200 |
| MSDS | msds/11308_1_86347_15_1.pdf |
| Use of | Properties Name medetomidine hydrochloride Synonym More Synonyms Medetomidine HCl Biological Activity Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease References [1]. Davies, M.F., et al., Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology, 2004. 29(2): p. 229-39. [2]. Ozdogan, U.K., et al., The involvement of alpha 2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice. Eur J Pharmacol, 2004. 497(2): p. 161-71. [3]. Menon, D.V., et al., Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans. J Am Coll Cardiol, 2007. 50(7): p. 626-33. Chemical & Physical Properties Exact Mass 236.108032 PSA 28.68000 LogP 3.98030 InChIKey VPNGEIHDPSLNMU-UHFFFAOYSA-N Storage condition Refrigerator Safety Information HS Code 2942000000 Synthetic Route 5-[1-(2,3-Dimet... CAS#:1021949-47-2 Medetomidine HCl CAS#:86347-15-1 Literature: "Joint Stock Company Grindeks" Patent: EP1918282 A1, 2008 ; Location in patent: Page/Page column 6 ; Medetomidine CAS#:86347-14-0 Medetomidine HCl CAS#:86347-15-1 2,3-Dimethylbro... CAS#:576-23-8 Medetomidine HCl CAS#:86347-15-1 Precursor & DownStream Precursor 3 CAS#:1021949-47-2 5-[1-(2,3-Dimet... CAS#:86347-14-0 Medetomidine CAS#:576-23-8 2,3-Dimethylbro... DownStream 1 CAS#:86347-14-0 Medetomidine |
| Transport Info | Product Name: Medetomidine HCl |
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