CAS Number13009-99-9
SynonymsSulfamylon Acetate; Benzenesulfonamide, 4-(aminomethyl)-, acetate (1:1); MFCD00072089; Mafenide Acetate; 4-(aminomethyl)-benzenesulfoamide monoacetate; Mafenide acetate; a-Amino-p-toluenesulfonamide Monoacetate; 4-(Aminomethyl)benzenesulfonamide acetate (1:1); p-(Aminomethyl)benzenesulfonamide Acetate; 4-Homosulfanilamide,Mafenide,Marfanil; acetic acid,4-(aminomethyl)benzenesulfonamide; EINECS 235-855-0; 4-(Aminomethyl)benzolsulfonamidacetat; 4-(aminomethyl)benzenesulfonamide acetate; Mafenide (Acetate)
Molecular FormulaC9H14N2O4S
Molecular Weight246.28
Purity98%
Boiling Point382ºC at 760 mmHg
Melting Point151-152ºC
Appearancecrystalline solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 13009-99-9 |
| Catalog No. | 2A-9011272 |
| Chinese Name | 醋酸磺胺米隆 |
| Synonyms | Sulfamylon Acetate; Benzenesulfonamide, 4-(aminomethyl)-, acetate (1:1); MFCD00072089; Mafenide Acetate; 4-(aminomethyl)-benzenesulfoamide monoacetate; Mafenide acetate; a-Amino-p-toluenesulfonamide Monoacetate; 4-(Aminomethyl)benzenesulfonamide acetate (1:1); p-(Aminomethyl)benzenesulfonamide Acetate; 4-Homosulfanilamide,Mafenide,Marfanil; acetic acid,4-(aminomethyl)benzenesulfonamide; EINECS 235-855-0; 4-(Aminomethyl)benzolsulfonamidacetat; 4-(aminomethyl)benzenesulfonamide acetate; Mafenide (Acetate) |
| Molecular Formula | C9H14N2O4S |
| Molecular Weight | 246.28 |
| Purity | 98 |
| Boiling Point | 382ºC at 760 mmHg |
| Melting Point | 151-152ºC |
| Appearance | crystalline solid |
| Storage Condition | Refrigerator |
| Application | Mafenide acetate is a sulfonamide antibiotic. |
| HTC | 2935009090 |
| PubChem ID | 329750301 |
| MDL Number | MFCD00072089 |
| SMILES | CC(O)=O.NCc1ccc(cc1)S(N)(=O)=O |
| InChI | 1S/C7H10N2O2S.C2H4O2/c8-5-6-1-3-7(4-2-6)12(9,10)11;1-2(3)4/h1-4H,5,8H2,(H2,9,10,11);1H3,(H,3,4) |
| InChI Key | UILOTUUZKGTYFQ-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/11272_1_13009_99_9.pdf |
| Bioactivity | Mafenide Acetate is a sulfonamide-type medication.Target: OthersMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9. Chemical & Physical Properties Boiling Point 382ºC at 760 mmHg Melting Point 151-152ºC Molecular Formula C9H14N2O4S Molecular Weight 246.283 Flash Point 184.8ºC Exact Mass 246.067429 PSA 131.86000 LogP 2.36500 Vapour Pressure 4.86E-06mmHg at 25°C Storage condition Refrigerator |
| Use of | Mafenide Acetate is a sulfonamide-type medication.Target: OthersMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Properties Name 4-(Aminomethyl)benzenesulfonamide acetate Synonym More Synonyms Mafenide Acetate Biological Activity Description Mafenide Acetate is a sulfonamide-type medication.Target: OthersMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9. Chemical & Physical Properties Molecular Formula C9H14N2O4S Exact Mass 246.067429 PSA 131.86000 LogP 2.36500 Storage condition Refrigerator |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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