Hydroxyprogesterone acetate structure, CAS 302-23-8

Hydroxyprogesterone acetate

CAS Number302-23-8

Synonyms17-Acetoxyprogesterone; 17α-Acetoxyprogesterone; 3,20-Dioxopregn-4-en-17-yl acetate; 17a-Hydroxy-progesterone acetate; 17ALPHA-ACETOXYPROGESTERONE; Prodox acetate; 17α-Hydroxy-4-pregnene-3,20-dione 17-acetate; 17-Hydroxypregn-4-ene-3,20-dione acetate; EINECS 206-119-6; 17-(Acetyloxy)pregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 17-hydroxy-, acetate; Hydroxyprogesterone acetate; Acetoxyprogesterone; ProgesteroneAcetate; 3,20-Dioxopregn-4-en-1-yl acetate; 17-Hydroxyprogesterone 17α-acetate; 4-Pregnen-17α-ol-3,20-dione acetate; MFCD00021156; 17-Hydroxyprogesterone acetate; 17α-Acetoxy-4-pregnene-3,20-dione; 17a-Hydroxyprogesterone Acetate

Molecular FormulaC23H32O4

Molecular Weight372.50

Purity95%

Density1.1±0.1 g/cm3

Boiling Point494.3±45.0 °C at 760 mmHg

Melting Point249-250ºC

Flash Point

Appearancewhite powder

EINECS

MSDSChineseEnglish

SymbolTransport

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Cat. No.: 2A-9010871 Purity: 95%
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Quality Control of [ 302-23-8 ] Purity: 95% SDS Specification MoL

Chemical & Physical Properties
CAS Number302-23-8
Catalog No.2A-9010871
Chinese Name醋羟孕酮
Synonyms17-Acetoxyprogesterone; 17α-Acetoxyprogesterone; 3,20-Dioxopregn-4-en-17-yl acetate; 17a-Hydroxy-progesterone acetate; 17ALPHA-ACETOXYPROGESTERONE; Prodox acetate; 17α-Hydroxy-4-pregnene-3,20-dione 17-acetate; 17-Hydroxypregn-4-ene-3,20-dione acetate; EINECS 206-119-6; 17-(Acetyloxy)pregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 17-hydroxy-, acetate; Hydroxyprogesterone acetate; Acetoxyprogesterone; ProgesteroneAcetate; 3,20-Dioxopregn-4-en-1-yl acetate; 17-Hydroxyprogesterone 17α-acetate; 4-Pregnen-17α-ol-3,20-dione acetate; MFCD00021156; 17-Hydroxyprogesterone acetate; 17α-Acetoxy-4-pregnene-3,20-dione; 17a-Hydroxyprogesterone Acetate
Molecular FormulaC23H32O4
Molecular Weight372.50
Purity95
Density1.1±0.1 g/cm3
Boiling Point494.3±45.0 °C at 760 mmHg
Melting Point249-250ºC
Appearancewhite powder
Storage ConditionRefrigerator
Application17α-Hydroxyprogesterone acetate has progesterone activity. 17α-hydroxyprogesterone acetate has anti-inflammatory effects at the maternal-fetal interface in mice [1][2].
PubChem ID329831526
MDL NumberMFCD00021156
SMILES[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O
InChI1S/C23H32O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h13,18-20H,5-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1
InChI KeyVTHUYJIXSMGYOQ-KOORYGTMSA-N
Beilstein/REAXYS2227870
NACRES CodeNA.24
UNSPSC41116107
Hazard SymbolsTransport
MSDSmsds/10871_1_302_23_8.pdf
Bioactivity17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2]. Related Catalog Research Areas >> Endocrinology Signaling Pathways >> Others >> Others In Vitro 17α-Hydroxyprogesterone (Delalutin) is not androgenic, and that it, like progesterone and certain other sex steroids, does not alter the development of nonreproductive organs[1]. References [1]. R E Seegmiller, et al. Evaluation of the teratogenic potential of delalutin (17 alpha-hydroxyprogesterone caproate) in mice. Teratology. 1983 Oct;28(2):201-8. [2]. Amy-Eunice Furcron, et al. Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface. Am J Obstet Gynecol. 2015 Dec;213(6):846.e1-846.e19. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 494.3±45.0 °C at 760 mmHg Melting Point 249-250ºC Molecular Formula C23H32O4 Molecular Weight 372.498 Flash Point 213.5±28.8 °C Exact Mass 372.230072 PSA 60.44000 LogP 3.41 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.541 InChIKey VTHUYJIXSMGYOQ-KOORYGTMSA-N SMILES CC(=O)OC1(C(C)=O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C Storage condition Refrigerator
Use of17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2]. Properties Name Progesterone Acetate Synonym More Synonyms Hydroxyprogesterone acetate Biological Activity Description 17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2]. Related Catalog Research Areas >> Endocrinology Signaling Pathways >> Others >> Others In Vitro 17α-Hydroxyprogesterone (Delalutin) is not androgenic, and that it, like progesterone and certain other sex steroids, does not alter the development of nonreproductive organs[1]. References [1]. R E Seegmiller, et al. Evaluation of the teratogenic potential of delalutin (17 alpha-hydroxyprogesterone caproate) in mice. Teratology. 1983 Oct;28(2):201-8. [2]. Amy-Eunice Furcron, et al. Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface. Am J Obstet Gynecol. 2015 Dec;213(6):846.e1-846.e19. Chemical & Physical Properties Molecular Formula C23H32O4 Exact Mass 372.230072 PSA 60.44000 Index of Refraction 1.541 InChIKey VTHUYJIXSMGYOQ-KOORYGTMSA-N Storage condition Refrigerator
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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