
CAS Number302-23-8
Synonyms17-Acetoxyprogesterone; 17α-Acetoxyprogesterone; 3,20-Dioxopregn-4-en-17-yl acetate; 17a-Hydroxy-progesterone acetate; 17ALPHA-ACETOXYPROGESTERONE; Prodox acetate; 17α-Hydroxy-4-pregnene-3,20-dione 17-acetate; 17-Hydroxypregn-4-ene-3,20-dione acetate; EINECS 206-119-6; 17-(Acetyloxy)pregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 17-hydroxy-, acetate; Hydroxyprogesterone acetate; Acetoxyprogesterone; ProgesteroneAcetate; 3,20-Dioxopregn-4-en-1-yl acetate; 17-Hydroxyprogesterone 17α-acetate; 4-Pregnen-17α-ol-3,20-dione acetate; MFCD00021156; 17-Hydroxyprogesterone acetate; 17α-Acetoxy-4-pregnene-3,20-dione; 17a-Hydroxyprogesterone Acetate
Molecular FormulaC23H32O4
Molecular Weight372.50
Purity95%
Density1.1±0.1 g/cm3
Boiling Point494.3±45.0 °C at 760 mmHg
Melting Point249-250ºC
Appearancewhite powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 302-23-8 |
| Catalog No. | 2A-9010871 |
| Chinese Name | 醋羟孕酮 |
| Synonyms | 17-Acetoxyprogesterone; 17α-Acetoxyprogesterone; 3,20-Dioxopregn-4-en-17-yl acetate; 17a-Hydroxy-progesterone acetate; 17ALPHA-ACETOXYPROGESTERONE; Prodox acetate; 17α-Hydroxy-4-pregnene-3,20-dione 17-acetate; 17-Hydroxypregn-4-ene-3,20-dione acetate; EINECS 206-119-6; 17-(Acetyloxy)pregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 17-hydroxy-, acetate; Hydroxyprogesterone acetate; Acetoxyprogesterone; ProgesteroneAcetate; 3,20-Dioxopregn-4-en-1-yl acetate; 17-Hydroxyprogesterone 17α-acetate; 4-Pregnen-17α-ol-3,20-dione acetate; MFCD00021156; 17-Hydroxyprogesterone acetate; 17α-Acetoxy-4-pregnene-3,20-dione; 17a-Hydroxyprogesterone Acetate |
| Molecular Formula | C23H32O4 |
| Molecular Weight | 372.50 |
| Purity | 95 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 494.3±45.0 °C at 760 mmHg |
| Melting Point | 249-250ºC |
| Appearance | white powder |
| Storage Condition | Refrigerator |
| Application | 17α-Hydroxyprogesterone acetate has progesterone activity. 17α-hydroxyprogesterone acetate has anti-inflammatory effects at the maternal-fetal interface in mice [1][2]. |
| PubChem ID | 329831526 |
| MDL Number | MFCD00021156 |
| SMILES | [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O |
| InChI | 1S/C23H32O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h13,18-20H,5-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1 |
| InChI Key | VTHUYJIXSMGYOQ-KOORYGTMSA-N |
| Beilstein/REAXYS | 2227870 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/10871_1_302_23_8.pdf |
| Bioactivity | 17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2]. Related Catalog Research Areas >> Endocrinology Signaling Pathways >> Others >> Others In Vitro 17α-Hydroxyprogesterone (Delalutin) is not androgenic, and that it, like progesterone and certain other sex steroids, does not alter the development of nonreproductive organs[1]. References [1]. R E Seegmiller, et al. Evaluation of the teratogenic potential of delalutin (17 alpha-hydroxyprogesterone caproate) in mice. Teratology. 1983 Oct;28(2):201-8. [2]. Amy-Eunice Furcron, et al. Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface. Am J Obstet Gynecol. 2015 Dec;213(6):846.e1-846.e19. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 494.3±45.0 °C at 760 mmHg Melting Point 249-250ºC Molecular Formula C23H32O4 Molecular Weight 372.498 Flash Point 213.5±28.8 °C Exact Mass 372.230072 PSA 60.44000 LogP 3.41 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.541 InChIKey VTHUYJIXSMGYOQ-KOORYGTMSA-N SMILES CC(=O)OC1(C(C)=O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C Storage condition Refrigerator |
| Use of | 17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2]. Properties Name Progesterone Acetate Synonym More Synonyms Hydroxyprogesterone acetate Biological Activity Description 17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2]. Related Catalog Research Areas >> Endocrinology Signaling Pathways >> Others >> Others In Vitro 17α-Hydroxyprogesterone (Delalutin) is not androgenic, and that it, like progesterone and certain other sex steroids, does not alter the development of nonreproductive organs[1]. References [1]. R E Seegmiller, et al. Evaluation of the teratogenic potential of delalutin (17 alpha-hydroxyprogesterone caproate) in mice. Teratology. 1983 Oct;28(2):201-8. [2]. Amy-Eunice Furcron, et al. Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface. Am J Obstet Gynecol. 2015 Dec;213(6):846.e1-846.e19. Chemical & Physical Properties Molecular Formula C23H32O4 Exact Mass 372.230072 PSA 60.44000 Index of Refraction 1.541 InChIKey VTHUYJIXSMGYOQ-KOORYGTMSA-N Storage condition Refrigerator |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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