CAS Number175463-14-6
SynonymsGemifloxactin; Gemifioxacin; gemifloxacin; Gemifloxacin Mesilate; 7-(3-Aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1
Molecular FormulaC18H20FN5O4
Molecular Weight485.49
Purity≥98 (HPLC)%
Density1.6±0.1 g/cm3
Boiling Point638.9±65.0 °C at 760 mmHg
Melting Point235-237°
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 175463-14-6 |
| Catalog No. | 2A-9010708 |
| Chinese Name | 吉米沙星 |
| Synonyms | Gemifloxactin; Gemifioxacin; gemifloxacin; Gemifloxacin Mesilate; 7-(3-Aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1 |
| Molecular Formula | C18H20FN5O4 |
| Molecular Weight | 485.49 |
| Purity | ≥98 (HPLC) |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 638.9±65.0 °C at 760 mmHg |
| Melting Point | 235-237° |
| Appearance | powder |
| Storage Condition | 2-8°C, sealed |
| Application | Gemifloxacin is a fluoroquinolone and an orally effective anti-pneumonia drug. Gemifloxacin has bactericidal activity against highly quinolone-resistant Streptococcus pneumoniae. Difloxacin can be use |
| HTC | 2933990090 |
| PubChem ID | 329825509 |
| MDL Number | MFCD08277637 |
| SMILES | CS(=O)(O)=O.OC(C1=CN(C2CC2)C3=NC(N4C/C(C(CN)C4)=N\OC)=C(F)C=C3C1=O)=O |
| InChI | 1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+; |
| InChI Key | JIYMVSQRGZEYAX-CWUUNJJBSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/10708_1_175463_14_6.pdf |
| Use of | Gemifloxacin, a fluoroquinolone, is a potent and orally active antipneumococcal agent. Gemifloxacin shows bactericidal activity against highly quinolone-resistant pneumococci.Gemifloxacin can be used for the research of respiratory infections, such as community-acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB)[1][2]. Properties Name gemifloxacin Synonym More Synonyms gemifloxacin Biological Activity Description Gemifloxacin, a fluoroquinolone, is a potent and orally active antipneumococcal agent. Gemifloxacin shows bactericidal activity against highly quinolone-resistant pneumococci.Gemifloxacin can be used for the research of respiratory infections, such as community-acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB)[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Yoo BK, et al. Gemifloxacin: a new fluoroquinolone approved for treatment of respiratory infections. Ann Pharmacother. 2004 Jul-Aug;38(7-8):1226-35. [2]. Davies TA, et al. Antipneumococcal activities of gemifloxacin compared to those of nine other agents. Antimicrob Agents Chemother. 2000 Feb;44(2):304-10. Chemical & Physical Properties Molecular Formula C18H20FN5O4 Exact Mass 389.149933 PSA 123.04000 Index of Refraction 1.735 InChIKey ZRCVYEYHRGVLOC-UHFFFAOYSA-N Safety Information HS Code 2933990090 Precursor & DownStream Precursor 8 CAS#:44981-94-4 N-(2-Cyanoethyl... CAS#:773826-73-6 tert-butyl 3-(a... CAS#:197143-33-2 tert-Butyl 3-cy... CAS#:175463-32-8 tert-Butyl 3-cy... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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