EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > Flunixin meglumine
Flunixin meglumine structure, CAS 42461-84-7

Flunixin meglumine

CAS Number42461-84-7

SynonymsFlunixin meglumine; MFCD01725419; EINECS 255-836-0; FLUNIXIN N-METHYLGLUCAMINE; 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt Banamine; Flunixin (meglumine)

Molecular FormulaC21H28O7N3F3

Molecular Weight491.46

Purity99%

Density1.403 g/cm3

Boiling Point378.7ºC at 760 mmHg

Melting Point136-138ºC

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9010564 Purity: 99%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 42461-84-7 ] Purity: 99% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number42461-84-7
Catalog No.2A-9010564
Chinese Name氟尼辛葡甲胺
SynonymsFlunixin meglumine; MFCD01725419; EINECS 255-836-0; FLUNIXIN N-METHYLGLUCAMINE; 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt Banamine; Flunixin (meglumine)
Molecular FormulaC21H28O7N3F3
Molecular Weight491.46
Purity99
Density1.403 g/cm3
Boiling Point378.7ºC at 760 mmHg
Melting Point136-138ºC
Appearancesolid
Water SolubilityH2O: freely soluble | soluble
Storage ConditionSealed, cool, dry storage
ApplicationFlunixin Meglumine is a COX inhibitor with anti-inflammatory and antipyretic activity.
MDL NumberMFCD01725419
SMILESCNCC(O)C(O)C(O)C(O)CO.Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F
InChIInChI=1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
InChI KeyMGCCHNLNRBULBU-WZTVWXICSA-N
Hazard SymbolsTransport
MSDSmsds/10564_1_42461_84_7.pdf
BioactivityFlunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity. Target: COXFlunixin meglumine is a potent, non-narcotic, non-steroidal analgesic agent with anti-inflammatory and antipyretic activity. It is a potent inhibitor of the enzyme cyclooxygenase. Flunixin meglumine therapy significantly (P less than or equal to 0.05) reduced rectal temperatures and quarter signs of inflammation and improved clinically graded depression when compared with these signs in saline solution-treated controls [1]. Flunixin meglumine was selective inhibitor of COX-1. Carprofen inhibited LPS-induction of iNOS. Carprofen and, to a lesser degree, flunixin meglumine had inhibitory effects on NFκB activation [2]. Related Catalog Research Areas >> Inflammation/Immunology Target COX-2:0.4 nM (IC50) COX-1:17 nM (IC50) References [1]. Cheng Z, et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation. 1998 Aug;22(4):353-66. [2]. Bryant, C.E., B.A. Farnfield, and H.J. Janicke, Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B. Am J Vet Res, 2003. 64(2): p. 211-5. Chemical & Physical Properties Density 1.403 g/cm3 Boiling Point 378.7ºC at 760 mmHg Melting Point 136-138ºC Molecular Formula C21H28F3N3O7 Molecular Weight 491.458 Flash Point 182.8ºC Exact Mass 491.187927 PSA 175.40000 LogP 0.95620 InChIKey MGCCHNLNRBULBU-WZTVWXICSA-N SMILES CNCC(O)C(O)C(O)C(O)CO.Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F Storage condition 0-6°C Water Solubility H2O: freely soluble | soluble
Use ofProperties Articles62 Name flunixin meglumine Synonym More Synonyms Flunixin Meglumine Biological Activity Related Catalog Research Areas >> Inflammation/Immunology COX-2:0.4 nM (IC50) COX-1:17 nM (IC50) References [1]. Cheng Z, et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation. 1998 Aug;22(4):353-66. [2]. Bryant, C.E., B.A. Farnfield, and H.J. Janicke, Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B. Am J Vet Res, 2003. 64(2): p. 211-5. Chemical & Physical Properties Molecular Formula C21H28F3N3O7 Exact Mass 491.187927 PSA 175.40000 LogP 0.95620 InChIKey MGCCHNLNRBULBU-WZTVWXICSA-N Water Solubility H2O: freely soluble | soluble
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
Related Products in Specialty Chemicals
Flumetalin62924-70-32A-9010557
Flumethrin69770-45-22A-9010558
Flumiclorac-pentyl87546-18-72A-9010559
Flunarizine52468-60-72A-9010561
Flunarizine Hydrochloride30484-77-62A-9010562
Fluocortolone152-97-62A-9010565
Fluometuron2164-17-22A-9010566
Fluorescein disodium salt518-47-82A-9010567
Fluoridamid47000-92-02A-9010568
Fluorometholone426-13-12A-0201796
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA