
CAS Number7704-67-8
SynonymsErythroMycin Thiocyanate CGMP; ErythroMicyn thiocyanate; ERYTHROMYCIN THIOCYANATE CP2000; erythromycin thiocynante; ERYTHROMYCIN THIOCYANATE NOT LESS THAN 750 U OF ERYFHROMYCIN PER MG; erythromycin A thiocyanate; ERYTHROMYCIN THIOCYNATE; erythromycin thiocyanante
Molecular FormulaC38H68N2O13S
Molecular Weight792.010
Purity98%
Boiling Point818.4ºC at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 7704-67-8 |
| Catalog No. | 2A-9010374 |
| Chinese Name | 硫氰酸红霉素 |
| Synonyms | ErythroMycin Thiocyanate CGMP; ErythroMicyn thiocyanate; ERYTHROMYCIN THIOCYANATE CP2000; erythromycin thiocynante; ERYTHROMYCIN THIOCYANATE NOT LESS THAN 750 U OF ERYFHROMYCIN PER MG; erythromycin A thiocyanate; ERYTHROMYCIN THIOCYNATE; erythromycin thiocyanante |
| Molecular Formula | C38H68N2O13S |
| Molecular Weight | 792.010 |
| Purity | 98 |
| Boiling Point | 818.4ºC at 760 mmHg |
| Application | Erythromycin thiocyanate is a macrolide antibiotic produced by the actinomycete Streptomyces erythreus and has broad antibacterial activity. Erythromycin thiocyanate acts by binding to the bacterial 5 |
| HTC | 2941500000 |
| SMILES | CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O.N#CS |
| InChI | InChI=1S/C37H67NO13.CHNS/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;2-1-3/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3H/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1 |
| InChI Key | WVRRTEYLDPNZHR-YZPBMOCRSA-N |
| Use of | Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1]. Properties Name Erythromycin thiocyanate Synonym More Synonyms Erythromycin Thicyanate Biological Activity Description Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial In Vitro Erythromycin inhibits growth of P. falciparum with IC50 and IC90 values of 58.2 μM and 104.0 μM, respectively[1]. References [1]. Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89. [2]. Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28. Chemical & Physical Properties Molecular Formula C38H68N2O13S Exact Mass 791.436951 PSA 256.50000 LogP 2.18288 InChIKey WVRRTEYLDPNZHR-YZPBMOCRSA-N Safety Information HS Code 2941500000 Synthetic Route Total: 1 Page Sodium thiocyanate CAS#:540-72-7 Erythromycin CAS#:114-07-8 Erythromycin Th... CAS#:7704-67-8 Literature: EP2301945 A1, ; Page/Page column 10 ; Precursor & DownStream Precursor 2 CAS#:540-72-7 Sodium thiocyanate CAS#:114-07-8 Erythromycin DownStream 1 CAS#:114-07-8 Erythromycin |
| Transport Info | Product Name: Erythromycin Thiocyanate |
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