CAS Number64840-90-0
Synonyms4-ethylphenyl-2-methyl-3-piperidinopropiopenone; 4'-ethyl-2-methyl-3-piperidino-propiophenone; EMPP; eperisone; MFCD00867679; Eperisone HCl
Molecular FormulaC17H25NO
Molecular Weight295.85
Purity98%
Density0.994 g/cm3
Boiling Point386.8ºC at 760 mmHg
Melting Point170-172ºC
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 64840-90-0 |
| Catalog No. | 2A-9010341 |
| Chinese Name | 乙哌立松 |
| Synonyms | 4-ethylphenyl-2-methyl-3-piperidinopropiopenone; 4'-ethyl-2-methyl-3-piperidino-propiophenone; EMPP; eperisone; MFCD00867679; Eperisone HCl |
| Molecular Formula | C17H25NO |
| Molecular Weight | 295.85 |
| Purity | 98 |
| Density | 0.994 g/cm3 |
| Boiling Point | 386.8ºC at 760 mmHg |
| Melting Point | 170-172ºC |
| Storage Condition | 2-8°C, sealed, dry |
| Application | Eperisone is an antispasmodic agent used to treat conditions characterized by muscle stiffness and pain. It works by relaxing skeletal and vascular smooth muscles, such as reducing muscle tone, improv |
| HTC | 2933399090 |
| MDL Number | C17H26ClNO |
| SMILES | CCc1ccc(C(=O)C(C)CN2CCCCC2)cc1 |
| InChI | InChI=1S/C17H25NO/c1-3-15-7-9-16(10-8-15)17(19)14(2)13-18-11-5-4-6-12-18/h7-10,14H,3-6,11-13H2,1-2H3 |
| InChI Key | SQUNAWUMZGQQJD-UHFFFAOYSA-N |
| MSDS | msds/10341_1_64840_90_0.pdf |
| Use of | Eperisone is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain. It works by relaxing both skeletal muscles and vascularsmooth muscles, thus demonstrating avariety of effects such as reduction ofmyotonia, improvement of circulationand suppression of the pain reflex. Eperisone is a centrally acting muscle relaxant inhibiting the pain reflex pathway, having a vasodilator effect[1][2 [3]. Properties Name 1-(4-ethylphenyl)-2-methyl-3-piperidin-1-ylpropan-1-one Synonym More Synonyms Eperisone Biological Activity Description Eperisone is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain. It works by relaxing both skeletal muscles and vascularsmooth muscles, thus demonstrating avariety of effects such as reduction ofmyotonia, improvement of circulationand suppression of the pain reflex. Eperisone is a centrally acting muscle relaxant inhibiting the pain reflex pathway, having a vasodilator effect[1][2 [3]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Cabitza P, et al. Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. Eur Rev Med Pharmacol Sci. 2008 Jul-Aug;12(4):229-35. [2]. Frandisco Colomer Rusinvol, et al. Effects of Two Diffferent Doses of Eperisone in the Treatment of Acute Low Back Pain. The Journal of Applied Research. [3]. Bavage S, et al. Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. Pharmacol Rep. 2016 Oct;68(5):903-12. Chemical & Physical Properties Molecular Formula C17H25NO Exact Mass 259.19400 PSA 20.31000 LogP 3.49160 InChIKey SQUNAWUMZGQQJD-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 1-Propanone, 1-(4-ethylphenyl)-2-methyl-3-(1-piperidinyl)- CAS REGISTRY NUMBER : 64840-90-0 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C17-H25-N-O HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in adrenal weight REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 20,1027,1992 Safety Information HS Code 2933399090 Synthetic Route Total: 1 Page Eperisone hydro... CAS#:56839-43-1 CAS#:64840-90-0 Precursor & DownStream Precursor 1 CAS#:56839-43-1 Eperisone hydro... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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