| Chemical & Physical Properties | |
|---|---|
| CAS Number | 165800-04-4 |
| Catalog No. | 2A-9010340 |
| Chinese Name | 依哌唑胺 |
| Synonyms | Eperezolid |
| Molecular Formula | C18H23O5N4F1 |
| Molecular Weight | 394.4 |
| Purity | 98.00 |
| Density | 1.37g/cm3 |
| Boiling Point | 701.2ºC at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | Eperezolid (PNU-100592) is an oxazolidinone antibiotic with good in vitro inhibitory properties. |
| HTC | 2934999090 |
| MDL Number | MFCD00941980 |
| SMILES | CC(=O)NCC1CN(c2ccc(N3CCN(C(=O)CO)CC3)c(F)c2)C(=O)O1 |
| InChI | InChI=1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1 |
| InChI Key | SIMWTRCFFSTNMG-AWEZNQCLSA-N |
| MSDS | msds/10340_1_165800_04_4.pdf |
| Use of | Properties Name N-[[(5S)-3-[3-fluoro-4-[4-(2-hydroxyacetyl)piperazin-1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide Synonym More Synonyms Eperezolid Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Rybak MJ, et al. Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus f [2]. Lin AH, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother. 1997 Oct;41(10):2127-31. [3]. Zhou CC, et al. 1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes. Antimicrob Agents Chemother. 2002 Mar;46(3):625-9. Chemical & Physical Properties Molecular Formula C18H23FN4O5 Exact Mass 394.16500 PSA 102.42000 LogP 0.38670 Index of Refraction 1.579 InChIKey SIMWTRCFFSTNMG-AWEZNQCLSA-N Storage condition 2-8℃ Safety Information HS Code 2934999090 Synthetic Route (S)-N-((3-(4-(4... CAS#:174649-08-2 Eperezolid CAS#:165800-04-4 Literature: Narina, Srinivasarao V.; Sudalai, Arumugam Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6799 - 6802 (S)-(+)-N-(oxir... CAS#:183805-10-9 Eperezolid CAS#:165800-04-4 Literature: Schaus, Scott E.; Jacobsen, Eric N. Tetrahedron Letters, 1996 , vol. 37, # 44 p. 7937 - 7940 (S)-N-[2-(Acety... CAS#:183905-31-9 Eperezolid CAS#:165800-04-4 Literature: Schaus, Scott E.; Jacobsen, Eric N. Tetrahedron Letters, 1996 , vol. 37, # 44 p. 7937 - 7940 Precursor & DownStream Precursor 8 CAS#:174649-08-2 (S)-N-((3-(4-(4... CAS#:183805-10-9 (S)-(+)-N-(oxir... CAS#:183905-31-9 (S)-N-[2-(Acety... CAS#:239438-47-2 (R)-3-(3-fluoro... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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