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Cleocin structure, CAS 58207-19-5

Cleocin

CAS Number58207-19-5

Synonymsclindamycin hydrochloride hydrate

Molecular FormulaC18H36Cl2N2O6S

Molecular Weight479.47

Purity98%

Density

Boiling Point647ºC at 760 mmHg

Melting Point143ºC

Flash Point

AppearanceWhite crystalline solid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9009831 Purity: 98%
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Quality Control of [ 58207-19-5 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number58207-19-5
Catalog No.2A-9009831
Chinese Name克林霉素盐酸盐 一水合物
Synonymsclindamycin hydrochloride hydrate
Molecular FormulaC18H36Cl2N2O6S
Molecular Weight479.47
Purity98
Boiling Point647ºC at 760 mmHg
Melting Point143ºC
AppearanceWhite crystalline solid
Water SolubilitySoluble in water
Storage ConditionRoom Temperature
ApplicationClindamycin hydrochloride monohydrate is an orally available protein synthesis inhibitor with the ability to express virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MI
HTC29419090
MDL NumberC18H36Cl2N2O6S
SMILESCCCC1CC(C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O)N(C)C1.Cl.O
InChI KeyKWMXKEGEOADCEQ-WNNJHRBUSA-N
MSDSmsds/9831_1_58207_19_5.pdf
BioactivityClindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla)[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Hodille E, et al. Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains. Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38. Chemical & Physical Properties Boiling Point 647ºC at 760 mmHg Melting Point 143ºC Molecular Formula C18H36Cl2N2O6S Molecular Weight 479.459 Flash Point 345.1ºC Exact Mass 478.167114 PSA 136.79000 LogP 1.45600 Index of Refraction 143 ° (C=2, H2O) InChIKey KWMXKEGEOADCEQ-WNNJHRBUSA-N SMILES CCCC1CC(C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O)N(C)C1.Cl.O Water Solubility Soluble in water
Use ofClindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla)[1]. Properties Articles47 Name Clindamycin Hydrochloride Monohydrate Synonym More Synonyms clindamycin hydrochloride Biological Activity Description Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla)[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Hodille E, et al. Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains. Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38. Chemical & Physical Properties Exact Mass 478.167114 PSA 136.79000 LogP 1.45600 InChIKey KWMXKEGEOADCEQ-WNNJHRBUSA-N Water Solubility Soluble in water
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified
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