
CAS Number77-38-3
SynonymsClorfenossamina [DCIT]; 2-(1-(4-Chlorophenyl)-1-phenylethoxy)-N,N-dimethylethanamine; Chlorphenoxamine [INN:BAN]; Clorfenoxamina [INN-Spanish]; {2-[1-(4-Chlor-phenyl)-1-phenyl-aethoxy]-aethyl}-dimethyl-amin; {2-[1-(4-chloro-phenyl)-1-phenyl-ethoxy]-ethyl}-dimethyl-amine; Chlorphenoxaminum [INN-Latin]; Contristamine; Chlorphenoxamine
Molecular FormulaC18H22O1N1Cl1
Molecular Weight303.83
Purity98%
Density1.093g/cm3
Boiling Point383.7ºC at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 77-38-3 |
| Catalog No. | 2A-9009755 |
| Chinese Name | 氯苯沙明 |
| Synonyms | Clorfenossamina [DCIT]; 2-(1-(4-Chlorophenyl)-1-phenylethoxy)-N,N-dimethylethanamine; Chlorphenoxamine [INN:BAN]; Clorfenoxamina [INN-Spanish]; {2-[1-(4-Chlor-phenyl)-1-phenyl-aethoxy]-aethyl}-dimethyl-amin; {2-[1-(4-chloro-phenyl)-1-phenyl-ethoxy]-ethyl}-dimethyl-amine; Chlorphenoxaminum [INN-Latin]; Contristamine; Chlorphenoxamine |
| Molecular Formula | C18H22O1N1Cl1 |
| Molecular Weight | 303.83 |
| Purity | 98 |
| Density | 1.093g/cm3 |
| Boiling Point | 383.7ºC at 760 mmHg |
| Storage Condition | 2-8°C |
| Application | Chlorphenoxamine is an antihistamine and anticholinergic drug used as an anti-Parkinson's disease drug. |
| HTC | 2922199090 |
| MDL Number | MFCD00866588 |
| SMILES | CN(C)CCOC(C)(c1ccccc1)c1ccc(Cl)cc1 |
| InChI | InChI=1S/C18H22ClNO.ClH/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16;/h4-12H,13-14H2,1-3H3;1H |
| InChI Key | KKHPNPMTPORSQE-UHFFFAOYSA-N |
| MSDS | msds/9755_1_77_38_3.pdf |
| Use of | Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. Target: Histamine Receptor Properties Name 2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine Synonym More Synonyms Chlorphenoxamine Biological Activity Description Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. Target: Histamine Receptor Related Catalog Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Chemical & Physical Properties Exact Mass 303.13900 PSA 12.47000 LogP 4.18170 Index of Refraction 1.551 InChIKey KKHPNPMTPORSQE-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Ethylamine, 2-(1-(p-chlorophenyl)-1-phenylethoxy)-N,N-dimethyl- CAS REGISTRY NUMBER : BEILSTEIN REFERENCE NO. : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C18-H22-Cl-N-O MOLECULAR WEIGHT : WISWESSER LINE NOTATION : GR DX1&R&O2N1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957 Safety Information Hazard Codes Xi HS Code 2922199090 Synthetic Route 4-Chlorobenzoyl... CAS#:122-01-0 Chlorphenoxamine CAS#:77-38-3 Literature: Tetrahedron Letters, , vol. 29, # 30 p. 3659 - 3662 Phenyllithium CAS#:591-51-5 Chlorphenoxamine CAS#:77-38-3 Literature: Tetrahedron Letters, , vol. 29, # 30 p. 3659 - 3662 4-Chlorobenzophenone CAS#:134-85-0 Chlorphenoxamine CAS#:77-38-3 Literature: Tetrahedron Letters, , vol. 29, # 30 p. 3659 - 3662 Precursor & DownStream Precursor 5 CAS#:122-01-0 4-Chlorobenzoyl... CAS#:591-51-5 Phenyllithium CAS#:134-85-0 4-Chlorobenzophenone CAS#:59767-24-7 1-(4-chlorophen... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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