CAS Number23325-78-2
SynonymsEINECS 239-773-6; Cephalexin monohydrate; MFCD00167148; Cefalexin（compacted）; Cefalexin Monohydrate
Molecular FormulaC16H19N3O5S
Molecular Weight365.40
Purity98%
Density1.5g/cm3
Boiling Point727.4ºC at 760 mmHg
AppearanceWhite crystalline solid with a bitter taste
EINECS239-773-6
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 23325-78-2 |
| Catalog No. | 2A-9009696 |
| Chinese Name | 头孢氨苄 |
| Synonyms | EINECS 239-773-6; Cephalexin monohydrate; MFCD00167148; Cefalexin（compacted）; Cefalexin Monohydrate |
| Molecular Formula | C16H19N3O5S |
| Molecular Weight | 365.40 |
| Purity | 98 |
| Density | 1.5g/cm3 |
| Boiling Point | 727.4ºC at 760 mmHg |
| Appearance | White crystalline solid with a bitter taste |
| Water Solubility | NH4OH 1 M: 50 mg/mL, clear, yellow |
| Storage Condition | 2-8°C |
| Application | Cefalexin monohydrate is a cephalosporin antibiotic. |
| EINECS | 239-773-6 |
| SMILES | S1[C@H]2N(C(=C(C1)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.O |
| InChI | 1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15-;/m1./s1 |
| InChI Key | AVGYWQBCYZHHPN-CYJZLJNKSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/9696_1_23325_78_2.pdf |
| Bioactivity | Cefalexin monohydrate is a cephalosporin antibiotic.Target: AntibacterialCefalexin (INN, BAN) or cephalexin (USAN, AAN) is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company. It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin. It was first marketed as Keflex (Lilly), and is marketed under several other trade names. As of 2008, cefalexin was the most popular cephalosporin antibiotic in the United States, with more than 25 million prescriptions of its generic versions alone, for US$255 million in sales (though less popular than two other antibiotics, amoxicillin and azithromycin, each with 50 million prescriptions per year).Cefalexin is marketed by generic pharmaceutical manufacturers under a wide range of brand names, including: Apo-Cephalex, Biocef, Cefanox, Ceforal, Cephabos, Cephalexin, Cephorum, Ceporex, Cilex, Ialex, Ibilex, Kefexin, Keflet, Keflex, Rekosporin, Keforal, Keftab, Keftal, Lopilexin, Larixin, Novo-Lexin, Ospexin, Tenkorex, Zephalexin, Panixine Disperdose, Rancef, Sialexin, Sporidex and Ulexin. A version of Keflex 750 mg capsules is marketed for twice-daily dosage, to improve compliance. However, it is not a sustained release formulation, and since it is more expensive than the older strengths, some physicians prescribe three 250 mg capsules to be taken twice daily, as a less expensive alternative. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Speight TM, et al. Cephalexin: a review of its antibacterial, pharmacological and therapeutic properties. Drugs. 1972;3(1):9-78. [2]. Tanrisever B, et al. Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine. Drugs. 1986;32 Suppl 3:1-16. Chemical & Physical Properties Density 1.5g/cm3 Boiling Point 727.4ºC at 760 mmHg Molecular Formula C16H19N3O5S Molecular Weight 383.850 Flash Point 393.7ºC Exact Mass 383.070648 PSA 147.26000 LogP 1.40970 Vapour Pressure 3.27E-22mmHg at 25°C Index of Refraction 154 ° (C=0.5, H2O) InChIKey AVGYWQBCYZHHPN-CYJZLJNKSA-N SMILES CC1=C(C(=O)O)N2C(=O)C(NC(=O)C(N)c3ccccc3)C2SC1.O Storage condition 2-8°C Water Solubility NH4OH 1 M: 50 mg/mL, clear, yellow |
| Use of | Properties Articles50 Name cephalexin monohydrate Synonym More Synonyms Cephalexin monohydrate Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Speight TM, et al. Cephalexin: a review of its antibacterial, pharmacological and therapeutic properties. Drugs. 1972;3(1):9-78. [2]. Tanrisever B, et al. Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine. Drugs. 1986;32 Suppl 3:1-16. Chemical & Physical Properties Molecular Formula C16H19N3O5S Exact Mass 383.070648 PSA 147.26000 LogP 1.40970 InChIKey AVGYWQBCYZHHPN-CYJZLJNKSA-N |
| Transport Info | Product name: Cephalexin monohydrate |
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