| Chemical & Physical Properties | |
|---|---|
| CAS Number | 63527-52-6 |
| Catalog No. | 2A-9009651 |
| Chinese Name | 头孢噻肟 |
| Synonyms | Cefotaxime; Zariviz; Cefabol; Cefotaxima acid; EINECS 264-299-1; Cephotaxime |
| Molecular Formula | C16H17N5O7S2 |
| Molecular Weight | 455.47 |
| Purity | 98 |
| Density | 1.8±0.1 g/cm3 |
| Melting Point | 162-163℃ |
| Appearance | white powder |
| Storage Condition | 2-8℃ |
| Application | Cefotaxime is a third-generation cephalosporin antibiotic with broad activity against Gram-positive and Gram-negative bacteria. |
| EINECS | 264-299-1 |
| HTC | 3003201100 |
| SMILES | [Na+].[s]1c(nc(c1)\C(=N\OC)\C(=N\[C@@H]2[C@@H]3SCC(=C(N3C2=O)C(=O)O)COC(=O)C)\[O-])N |
| InChI | 1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m0./s1 |
| InChI Key | AZZMGZXNTDTSME-XJTDMATHSA-M |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/9651_1_63527_52_6.pdf |
| Use of | Cefotaxime, a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria[1][2][3][4]. Properties Articles27 Name cefotaxime Synonym More Synonyms cefotaxime Biological Activity Description Cefotaxime, a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria[1][2][3][4]. Related Catalog Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial References [1]. Hee-Chang Jang, et al. In vivo efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus sepsis. PLoS One. 2014 Jun 30;9(6):e101118. [2]. Woodfield JC, et al. A comparison of the prophylactic efficacy of ceftriaxone and cefotaxime in abdominal surgery. Am J Surg. 2003 Jan;185(1):45-9. [3]. Scholz H, et al. Prospective comparison of ceftriaxone and cefotaxime for the short-term treatment of bacterial meningitis in children. Chemotherapy. 1998 Mar-Apr;44(2):142-7. [4]. Gums JG, et al. Differences between ceftriaxone and cefotaxime: microbiological inconsistencies. Ann Pharmacother. 2008 Jan;42(1):71-9. Chemical & Physical Properties Molecular Formula C16H17N5O7S2 Exact Mass 455.056946 PSA 227.05000 Index of Refraction 1.779 InChIKey GPRBEKHLDVQUJE-FMXWCYLFSA-N Storage condition 2-8℃ Safety Information HS Code 3003201100 Synthetic Route (6R,7R)-3-(acet... 64486-19-7 cefotaxime 63527-52-6 (6R,7R)-3-(acet... 71754-15-9 17356-08-0 cefotaxime 63527-52-6 S-2-Benzothiazo... 80756-85-0 7-Aminocephalos... cefotaxime 63527-52-6 2-Mercaptobenzo... Precursor & DownStream Precursor 8 CAS#:64486-19-7 (6R,7R)-3-(acet... CAS#:71754-15-9 (6R,7R)-3-(acet... CAS#:80756-85-0 S-2-Benzothiazo... CAS#:957-68-6 7-Aminocephalos... DownStream 5 CAS#:80370-57-6 CAS#:87239-81-4 Cefpodoxime Proxetil CAS#:84957-29-9 CAS#:84957-30-2 Cefquinome |
| Transport Info | Product Name: Cefotaxime |
| Related Products in API & Advanced Intermediates | ||
|---|---|---|
| Cefazolin | 25953-19-9 | 2A-9009627 |
| Cefdinir | 91832-40-5 | 2A-9009631 |
| Cefepime | 88040-23-7 | 2A-9009633 |
| Cefepime hydrochloride | 123171-59-5 | 2A-9009634 |
| Cefixime | 79350-37-1 | 2A-9009638 |
| Cefotaxime sodium | 64485-93-4 | 2A-9009652 |
| Ceftazidime | 72558-82-8 | 2A-9009670 |
| Ceftazidime dihydrochloride | 73547-70-3 | 2A-9009671 |
| Ceftriaxone sodium | 104376-79-6 | 2A-9009681 |
| Ceftriaxone sodium | 73384-59-5 | 2A-9009682 |
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