CAS Number35543-24-9
SynonymsBuflocit; Buflomedilhydrochlorid; Provas; Buflomedil hydrochloride; Buflomedil HCl; fenoterol-Cl; EINECS 252-611-9; MFCD00078965; 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one hydrochloride (1:1); ll1656; (2,4,6-Trimethoxyphenyl) (3-Pyrrolidinopropyl) Ketone Hydrochloride; 2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone Hydrochloride; 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-, hydrochloride (1:1); 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one hydrochloride; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone hydrochloride; Irrodan; 1-[4-Oxo-4-(2,4,6-trimethoxyphenyl)butyl]pyrrolidinium chloride; bufedil; Buflan; Lofton; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone; Buflonat; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butano
Molecular FormulaC17H26O4N1Cl1
Molecular Weight343.85
Purity98%
Boiling Point454.5ºC at 760 mmHg
Melting Point193°C
AppearanceWhite-off-white crystal-powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 35543-24-9 |
| Catalog No. | 2A-9009477 |
| Chinese Name | 盐酸丁咯地尔 |
| Synonyms | Buflocit; Buflomedilhydrochlorid; Provas; Buflomedil hydrochloride; Buflomedil HCl; fenoterol-Cl; EINECS 252-611-9; MFCD00078965; 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one hydrochloride (1:1); ll1656; (2,4,6-Trimethoxyphenyl) (3-Pyrrolidinopropyl) Ketone Hydrochloride; 2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone Hydrochloride; 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-, hydrochloride (1:1); 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one hydrochloride; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone hydrochloride; Irrodan; 1-[4-Oxo-4-(2,4,6-trimethoxyphenyl)butyl]pyrrolidinium chloride; bufedil; Buflan; Lofton; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone; Buflonat; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butano |
| Molecular Formula | C17H26O4N1Cl1 |
| Molecular Weight | 343.85 |
| Purity | 98 |
| Boiling Point | 454.5ºC at 760 mmHg |
| Melting Point | 193°C |
| Appearance | White-off-white crystal-powder |
| Storage Condition | The warehouse is ventilated and dried at low tempe |
| Application | Buflomedil hydrochloride is a vasodilator that can act on a series of symptoms caused by peripheral arterial disease. |
| HTC | 2933990090 |
| MDL Number | MFCD00078965 |
| SMILES | COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1.Cl |
| InChI | InChI=1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H |
| InChI Key | ZDPACSAHMZADFZ-UHFFFAOYSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/9477_1_35543_24_9.pdf |
| Bioactivity | Buflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.Target: OthersBuflomedil is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. In the EU, buflomedil, a vasoactive agent, was indicated for treatment of PAOD symptoms, specifically in patients with stage II PAOD who experience severe pain when walking even relatively short distances. Buflomedil is not currently approved by the US Food and Drug Administration for use in the United States. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others References [1]. http://www.medscape.com/viewarticle/753768 Chemical & Physical Properties Boiling Point 454.5ºC at 760 mmHg Melting Point 193°C Molecular Formula C17H26ClNO4 Molecular Weight 343.846 Flash Point 228.7ºC Exact Mass 343.155029 PSA 48.00000 LogP 3.51100 InChIKey ZDPACSAHMZADFZ-UHFFFAOYSA-N SMILES COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1.Cl |
| Use of | Buflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.Target: OthersBuflomedil is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. In the EU, buflomedil, a vasoactive agent, was indicated for treatment of PAOD symptoms, specifically in patients with stage II PAOD who experience severe pain when walking even relatively short distances. Buflomedil is not currently approved by the US Food and Drug Administration for use in the United States. Properties Articles26 Name 1-[3-(2,4,6-Trimethoxybenzoyl)propyl]pyrrolidinium chloride Synonym More Synonyms Buflomedil hydrochloride Biological Activity Description Buflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.Target: OthersBuflomedil is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. In the EU, buflomedil, a vasoactive agent, was indicated for treatment of PAOD symptoms, specifically in patients with stage II PAOD who experience severe pain when walking even relatively short distances. Buflomedil is not currently approved by the US Food and Drug Administration for use in the United States. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others References [1]. http://www.medscape.com/viewarticle/753768 Chemical & Physical Properties Exact Mass 343.155029 PSA 48.00000 LogP 3.51100 InChIKey ZDPACSAHMZADFZ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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