CAS Number55837-25-7
Synonyms4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone; Buflomedil; BufluomedilHcl; EINECS 259-851-3; AURORA KA-850; 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one; 4-pyrrolidin-1-yl-1-[2,4,6-tris(methyloxy)phenyl]butan-1-one; 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one; MFCD00242740; 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-on; (2,4,6-Trimethoxyphenyl) (3-Pyrrolidinopropyl) Ketone
Molecular FormulaC17H25NO4
Molecular Weight343.85
Purity98%
Density1.1±0.1 g/cm3
Boiling Point454.5±45.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 55837-25-7 |
| Catalog No. | 2A-9009476 |
| Chinese Name | 丁洛地尔 |
| Synonyms | 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone; Buflomedil; BufluomedilHcl; EINECS 259-851-3; AURORA KA-850; 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one; 4-pyrrolidin-1-yl-1-[2,4,6-tris(methyloxy)phenyl]butan-1-one; 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one; MFCD00242740; 4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-on; (2,4,6-Trimethoxyphenyl) (3-Pyrrolidinopropyl) Ketone |
| Molecular Formula | C17H25NO4 |
| Molecular Weight | 343.85 |
| Purity | 98 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 454.5±45.0 °C at 760 mmHg |
| Application | Buflomedil is a vasoactive agent. Buflomedil is an alpha1-, alpha2-adrenolytic compound. Buflomedil is used in the study of cardiovascular diseases, such as peripheral vascular disease. |
| HTC | 29339990 |
| PubChem ID | 329831476 |
| MDL Number | MFCD00078965 |
| SMILES | Cl.COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1 |
| InChI | 1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H |
| InChI Key | ZDPACSAHMZADFZ-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/9476_1_55837_25_7.pdf |
| Use of | Buflomedil is an orally active vasoactive agent. Buflomedil is an α1-, α2-adrenolytic compound. Buflomedil can be used for research of cardiovascular disease, such as peripheral vascular disease[1][2]. Properties Name Buflomedil Synonym More Synonyms Buflomedil Biological Activity Description Buflomedil is an orally active vasoactive agent. Buflomedil is an α1-, α2-adrenolytic compound. Buflomedil can be used for research of cardiovascular disease, such as peripheral vascular disease[1][2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others References [1]. de Backer TL, et al. Buflomedil for intermittent claudication. Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD000988. [2]. Limbs International Medicinal Buflomedil (LIMB) Study Group; Leizorovicz A, Becker F. Oral buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease: a randomized, placebo-controlled, 4-year study. Circulation. 2008 Feb 12;117(6):816-22. Chemical & Physical Properties Molecular Formula C17H25NO4 Exact Mass 307.178345 PSA 48.00000 Index of Refraction 1.520 InChIKey OWYLAEYXIQKAOL-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)- CAS REGISTRY NUMBER : 55837-25-7 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C17-H25-N-O4 MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Rodent - mouse Fibroblast DOSE/DURATION : 1080 umol/L REFERENCE : TIVIEQ Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 4,751,1990 Safety Information Hazard Codes Xn Safety Phrases 26-36 WGK Germany 3 RTECS EL9885000 HS Code 29339990 |
| Transport Info | Product name: Buflomedil |
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